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Patient-Derived Blood-Brain Barrier Model for Screening Copper Bis(thiosemicarbazone) Complexes as Potential Therapeutics in Alzheimer's Disease.
ACS Chem Neurosci. 2024 Apr 3;15(7):1432-1455. doi: 10.1021/acschemneuro.3c00743. Epub 2024 Mar 13.
ACS Chem Neurosci. 2024.
PMID: 38477556
A sporadic Alzheimer's blood-brain barrier model for developing ultrasound-mediated delivery of Aducanumab and anti-Tau antibodies.
Wasielewska JM, Chaves JCS, Johnston RL, Milton LA, Hernández D, Chen L, Song J, Lee W, Leinenga G, Nisbet RM, Pébay A, Götz J, White AR, Oikari LE.
Wasielewska JM, et al. Among authors: chaves jcs.
Theranostics. 2022 Sep 25;12(16):6826-6847. doi: 10.7150/thno.72685. eCollection 2022.
Theranostics. 2022.
PMID: 36276649
Free PMC article.
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Blood-brain barrier transporters: An overview of function, dysfunction in Alzheimer's disease and strategies for treatment.
Chaves JCS, Dando SJ, White AR, Oikari LE.
Chaves JCS, et al.
Biochim Biophys Acta Mol Basis Dis. 2024 Feb;1870(2):166967. doi: 10.1016/j.bbadis.2023.166967. Epub 2023 Nov 24.
Biochim Biophys Acta Mol Basis Dis. 2024.
PMID: 38008230
Review.
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Alzheimer's disease brain endothelial-like cells reveal differential drug transporter expression and modulation by potentially therapeutic focused ultrasound.
Chaves JCS, Wasielewska JM, Cuní-López C, Rantanen LM, Lee S, Koistinaho J, White AR, Oikari LE.
Chaves JCS, et al.
Neurotherapeutics. 2024 Jan;21(1):e00299. doi: 10.1016/j.neurot.2023.10.009. Epub 2023 Dec 19.
Neurotherapeutics. 2024.
PMID: 38241156
Free PMC article.
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Differential Cytokine Responses of APOE3 and APOE4 Blood-brain Barrier Cell Types to SARS-CoV-2 Spike Proteins.
Chaves JCS, Milton LA, Stewart R, Senapati T, Rantanen LM, Wasielewska JM, Lee S, Hernández D, McInnes L, Quek H, Pébay A, Donnelly PS, White AR, Oikari LE.
Chaves JCS, et al.
J Neuroimmune Pharmacol. 2024 May 21;19(1):22. doi: 10.1007/s11481-024-10127-9.
J Neuroimmune Pharmacol. 2024.
PMID: 38771543
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microRNAs expression correlates with levels of APP, DYRK1A, hyperphosphorylated Tau and BDNF in the hippocampus of a mouse model for Down syndrome during ageing.
Chaves JCS, Machado FT, Almeida MF, Bacovsky TB, Ferrari MFR.
Chaves JCS, et al.
Neurosci Lett. 2020 Jan 1;714:134541. doi: 10.1016/j.neulet.2019.134541. Epub 2019 Oct 9.
Neurosci Lett. 2020.
PMID: 31605772
Free article.
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BDNF trafficking and signaling impairment during early neurodegeneration is prevented by moderate physical activity.
Almeida MF, Chaves RS, Silva CM, Chaves JCS, Melo KP, Ferrari MFR.
Almeida MF, et al. Among authors: chaves jcs.
IBRO Rep. 2016 Aug 30;1:19-31. doi: 10.1016/j.ibror.2016.08.001. eCollection 2016 Dec.
IBRO Rep. 2016.
PMID: 30135925
Free PMC article.
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