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Proteomic analysis of host cell protein fouling during bioreactor harvesting.
Biotechnol Prog. 2024 Mar 13:e3453. doi: 10.1002/btpr.3453. Online ahead of print.
Biotechnol Prog. 2024.
PMID: 38477450
Evaluation of a single-use disk stack centrifuge for improved efficiency and sustainability at 1000 L GMP manufacturing scale.
Walker J, Lam Y, Loman A, Smelko JP, Rohr M.
Walker J, et al. Among authors: smelko jp.
Biotechnol Bioeng. 2023 Nov;120(11):3347-3356. doi: 10.1002/bit.28519. Epub 2023 Aug 4.
Biotechnol Bioeng. 2023.
PMID: 37539666
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Use of scanning electron microscopy and energy dispersive X-ray spectroscopy to identify key fouling species during alternating tangential filtration.
Sundar V, Zhang D, Qian X, Wickramasinghe SR, Smelko JP, Carbrello C, Jabbour Al Maalouf Y, Zydney AL.
Sundar V, et al. Among authors: smelko jp.
Biotechnol Prog. 2023 May-Jun;39(3):e3336. doi: 10.1002/btpr.3336. Epub 2023 Mar 7.
Biotechnol Prog. 2023.
PMID: 36825399
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Glucose monitoring and adaptive feeding of mammalian cell culture in the presence of strong autofluorescence by near infrared Raman spectroscopy.
Matthews TE, Smelko JP, Berry B, Romero-Torres S, Hill D, Kshirsagar R, Wiltberger K.
Matthews TE, et al. Among authors: smelko jp.
Biotechnol Prog. 2018 Nov;34(6):1574-1580. doi: 10.1002/btpr.2711. Epub 2018 Oct 3.
Biotechnol Prog. 2018.
PMID: 30281947
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Performance of high intensity fed-batch mammalian cell cultures in disposable bioreactor systems.
Smelko JP, Wiltberger KR, Hickman EF, Morris BJ, Blackburn TJ, Ryll T.
Smelko JP, et al.
Biotechnol Prog. 2011 Sep-Oct;27(5):1358-64. doi: 10.1002/btpr.634. Epub 2011 May 27.
Biotechnol Prog. 2011.
PMID: 21626722
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Effects of solution environment on mammalian cell fermentation broth properties: enhanced impurity removal and clarification performance.
Westoby M, Chrostowski J, de Vilmorin P, Smelko JP, Romero JK.
Westoby M, et al. Among authors: smelko jp.
Biotechnol Bioeng. 2011 Jan;108(1):50-8. doi: 10.1002/bit.22923.
Biotechnol Bioeng. 2011.
PMID: 20812295
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