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The Role of ZO-2 in Modulating JAM-A and γ-Actin Junctional Recruitment, Apical Membrane and Tight Junction Tension, and Cell Response to Substrate Stiffness and Topography.
Pinto-Dueñas DC, Hernández-Guzmán C, Marsch PM, Wadurkar AS, Martín-Tapia D, Alarcón L, Vázquez-Victorio G, Méndez-Méndez JV, Chanona-Pérez JJ, Nangia S, González-Mariscal L. Pinto-Dueñas DC, et al. Among authors: alarcon l. Int J Mol Sci. 2024 Feb 20;25(5):2453. doi: 10.3390/ijms25052453. Int J Mol Sci. 2024. PMID: 38473701 Free PMC article.
Activation of the Ca2+ sensing receptor and the PKC/WNK4 downstream signaling cascade induces incorporation of ZO-2 to tight junctions and its separation from 14-3-3.
Amaya E, Alarcón L, Martín-Tapia D, Cuellar-Pérez F, Cano-Cortina M, Ortega-Olvera JM, Cisneros B, Rodriguez AJ, Gamba G, González-Mariscal L. Amaya E, et al. Among authors: alarcon l. Mol Biol Cell. 2019 Aug 15;30(18):2377-2398. doi: 10.1091/mbc.E18-09-0591. Epub 2019 Jul 18. Mol Biol Cell. 2019. PMID: 31318316 Free PMC article.
Tight junction proteins ZO-1, ZO-2, and occludin along isolated renal tubules.
Gonzalez-Mariscal L, Namorado MC, Martin D, Luna J, Alarcon L, Islas S, Valencia L, Muriel P, Ponce L, Reyes JL. Gonzalez-Mariscal L, et al. Among authors: alarcon l. Kidney Int. 2000 Jun;57(6):2386-402. doi: 10.1046/j.1523-1755.2000.00098.x. Kidney Int. 2000. PMID: 10844608 Free article.
ZO-2 silencing induces renal hypertrophy through a cell cycle mechanism and the activation of YAP and the mTOR pathway.
Domínguez-Calderón A, Ávila-Flores A, Ponce A, López-Bayghen E, Calderón-Salinas JV, Luis Reyes J, Chávez-Munguía B, Segovia J, Angulo C, Ramírez L, Gallego-Gutiérrez H, Alarcón L, Martín-Tapia D, Bautista-García P, González-Mariscal L. Domínguez-Calderón A, et al. Among authors: alarcon l. Mol Biol Cell. 2016 May 15;27(10):1581-95. doi: 10.1091/mbc.E15-08-0598. Epub 2016 Mar 23. Mol Biol Cell. 2016. PMID: 27009203 Free PMC article.
201 results