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In silico investigation of the role of miRNAs in a possible developmental origin of prostate cancer in F1 and F2 offspring of mothers exposed to a phthalate mixture.
Environ Toxicol. 2024 Jun;39(6):3523-3536. doi: 10.1002/tox.24181. Epub 2024 Mar 11.
Environ Toxicol. 2024.
PMID: 38465474
Integrated transcriptome and proteome analysis indicates potential biomarkers of prostate cancer in offspring of pregnant rats exposed to a phthalate mixture during gestation and lactation.
Aquino AM, Alonso-Costa LG, Santos SAA, Rocha VA, Barbisan LF, Bedrat A, Justulin LA, Flaws JA, Lemos B, Scarano WR.
Aquino AM, et al. Among authors: alonso costa lg.
Chemosphere. 2023 Nov;341:140020. doi: 10.1016/j.chemosphere.2023.140020. Epub 2023 Sep 8.
Chemosphere. 2023.
PMID: 37690569
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Multigenerational Effects of an Environmentally Relevant Phthalate Mixture on Reproductive Parameters and Ovarian miRNA Expression in Female Rats.
Gonsioroski AV, Aquino AM, Alonso-Costa LG, Barbisan LF, Scarano WR, Flaws JA.
Gonsioroski AV, et al. Among authors: alonso costa lg.
Toxicol Sci. 2022 Aug 25;189(1):91-106. doi: 10.1093/toxsci/kfac066.
Toxicol Sci. 2022.
PMID: 35762964
Free PMC article.
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Prenatal exposure to a mixture of different phthalates increases the risk of mammary carcinogenesis in F1 female offspring.
de Freitas T, Zapaterini JR, Moreira CM, de Aquino AM, Alonso-Costa LG, Bidinotto LT, Kass L, Flaws JA, Scarano WR, Barbisan LF.
de Freitas T, et al. Among authors: alonso costa lg.
Food Chem Toxicol. 2021 Oct;156:112519. doi: 10.1016/j.fct.2021.112519. Epub 2021 Aug 21.
Food Chem Toxicol. 2021.
PMID: 34428494
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Exposure to an Environmentally Relevant Phthalate Mixture During Prostate Development Induces MicroRNA Upregulation and Transcriptome Modulation in Rats.
Scarano WR, Bedrat A, Alonso-Costa LG, Aquino AM, Fantinatti BEA, Justulin LA, Barbisan LF, Freire PP, Flaws JA, Lemos B.
Scarano WR, et al. Among authors: alonso costa lg.
Toxicol Sci. 2019 Sep 1;171(1):84-97. doi: 10.1093/toxsci/kfz141.
Toxicol Sci. 2019.
PMID: 31199487
Free PMC article.
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