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A phase 1 trial of human telomerase reverse transcriptase (hTERT) vaccination combined with therapeutic strategies to control immune-suppressor mechanisms.
Zareian N, Eremin O, Pandha H, Baird R, Kwatra V, Funingana G, Verma C, Choy D, Hargreaves S, Moghimi P, Shepherd A, Lobo DN, Eremin J, Farzaneh F, Kordasti S, Spicer J. Zareian N, et al. Among authors: verma c. Exp Biol Med (Maywood). 2024 Jan 31;249:10021. doi: 10.3389/ebm.2024.10021. eCollection 2024. Exp Biol Med (Maywood). 2024. PMID: 38463391 Free PMC article. Clinical Trial.
Generation in vivo of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCs.
Aloysius MM, Mc Kechnie AJ, Robins RA, Verma C, Eremin JM, Farzaneh F, Habib NA, Bhalla J, Hardwick NR, Satthaporn S, Sreenivasan T, El-Sheemy M, Eremin O. Aloysius MM, et al. Among authors: verma c. J Transl Med. 2009 Mar 19;7:18. doi: 10.1186/1479-5876-7-18. J Transl Med. 2009. PMID: 19298672 Free PMC article.
Crucial Contributions by T Lymphocytes (Effector, Regulatory, and Checkpoint Inhibitor) and Cytokines (TH1, TH2, and TH17) to a Pathological Complete Response Induced by Neoadjuvant Chemotherapy in Women with Breast Cancer.
Kaewkangsadan V, Verma C, Eremin JM, Cowley G, Ilyas M, Eremin O. Kaewkangsadan V, et al. Among authors: verma c. J Immunol Res. 2016;2016:4757405. doi: 10.1155/2016/4757405. Epub 2016 Sep 29. J Immunol Res. 2016. PMID: 27777963 Free PMC article.
Tumour-draining axillary lymph nodes in patients with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC): the crucial contribution of immune cells (effector, regulatory) and cytokines (Th1, Th2) to immune-mediated tumour cell death induced by NAC.
Kaewkangsadan V, Verma C, Eremin JM, Cowley G, Ilyas M, Eremin O. Kaewkangsadan V, et al. Among authors: verma c. BMC Cancer. 2018 Feb 2;18(1):123. doi: 10.1186/s12885-018-4044-z. BMC Cancer. 2018. PMID: 29390966 Free PMC article.
Natural killer (NK) cell profiles in blood and tumour in women with large and locally advanced breast cancer (LLABC) and their contribution to a pathological complete response (PCR) in the tumour following neoadjuvant chemotherapy (NAC): differential restoration of blood profiles by NAC and surgery.
Verma C, Kaewkangsadan V, Eremin JM, Cowley GP, Ilyas M, El-Sheemy MA, Eremin O. Verma C, et al. J Transl Med. 2015 Jun 4;13:180. doi: 10.1186/s12967-015-0535-8. J Transl Med. 2015. PMID: 26040463 Free PMC article.
Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC.
Verma C, Eremin JM, Robins A, Bennett AJ, Cowley GP, El-Sheemy MA, Jibril JA, Eremin O. Verma C, et al. J Transl Med. 2013 Jan 15;11:16. doi: 10.1186/1479-5876-11-16. J Transl Med. 2013. PMID: 23320561 Free PMC article.
The Differential Contribution of the Innate Immune System to a Good Pathological Response in the Breast and Axillary Lymph Nodes Induced by Neoadjuvant Chemotherapy in Women with Large and Locally Advanced Breast Cancers.
Kaewkangsadan V, Verma C, Eremin JM, Cowley G, Ilyas M, Satthaporn S, Eremin O. Kaewkangsadan V, et al. Among authors: verma c. J Immunol Res. 2017;2017:1049023. doi: 10.1155/2017/1049023. Epub 2017 Aug 23. J Immunol Res. 2017. PMID: 28913366 Free PMC article.
Ex vivo recovery and activation of dysfunctional, anergic, monocyte-derived dendritic cells from patients with operable breast cancer: critical role of IFN-alpha.
Satthaporn S, Aloysius MM, Robins RA, Verma C, Chuthapisith S, McKechnie AJ, El-Sheemy M, Vassanasiri W, Valerio D, Clark D, Jibril JA, Eremin O. Satthaporn S, et al. Among authors: verma c. BMC Immunol. 2008 Jun 27;9:32. doi: 10.1186/1471-2172-9-32. BMC Immunol. 2008. PMID: 18588665 Free PMC article.
510 results