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Roflumilast inhibits tumor growth and migration in STK11/LKB1 deficient pancreatic cancer.
Zhang S, Yun D, Yang H, Eckstein M, Elbait GD, Zhou Y, Lu Y, Yang H, Zhang J, Dörflein I, Britzen-Laurent N, Pfeffer S, Stemmler MP, Dahl A, Mukhopadhyay D, Chang D, He H, Zeng S, Lan B, Frey B, Hampel C, Lentsch E, Gollavilli PN, Büttner C, Ekici AB, Biankin A, Schneider-Stock R, Ceppi P, Grützmann R, Pilarsky C. Zhang S, et al. Among authors: stemmler mp. Cell Death Discov. 2024 Mar 9;10(1):124. doi: 10.1038/s41420-024-01890-y. Cell Death Discov. 2024. PMID: 38461159 Free PMC article.
Metabolic impairment of non-small cell lung cancers by mitochondrial HSPD1 targeting.
Parma B, Ramesh V, Gollavilli PN, Siddiqui A, Pinna L, Schwab A, Marschall S, Zhang S, Pilarsky C, Napoli F, Volante M, Urbanczyk S, Mielenz D, Schrøder HD, Stemmler M, Wurdak H, Ceppi P. Parma B, et al. J Exp Clin Cancer Res. 2021 Aug 7;40(1):248. doi: 10.1186/s13046-021-02049-8. J Exp Clin Cancer Res. 2021. PMID: 34364401 Free PMC article.
The EMT transcription factor ZEB1 governs a fitness-promoting but vulnerable DNA replication stress response.
Schuhwerk H, Kleemann J, Gupta P, van Roey R, Armstark I, Kreileder M, Feldker N, Ramesh V, Hajjaj Y, Fuchs K, Mahapatro M, Hribersek M, Volante M, Groenewoud A, Engel FB, Ceppi P, Eckstein M, Hartmann A, Müller F, Kroll T, Stemmler MP, Brabletz S, Brabletz T. Schuhwerk H, et al. Among authors: stemmler mp. Cell Rep. 2022 Dec 13;41(11):111819. doi: 10.1016/j.celrep.2022.111819. Cell Rep. 2022. PMID: 36516781 Free article.
The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer.
Krebs AM, Mitschke J, Lasierra Losada M, Schmalhofer O, Boerries M, Busch H, Boettcher M, Mougiakakos D, Reichardt W, Bronsert P, Brunton VG, Pilarsky C, Winkler TH, Brabletz S, Stemmler MP, Brabletz T. Krebs AM, et al. Among authors: stemmler mp. Nat Cell Biol. 2017 May;19(5):518-529. doi: 10.1038/ncb3513. Epub 2017 Apr 17. Nat Cell Biol. 2017. PMID: 28414315
Neutrophil extracellular traps drive epithelial-mesenchymal transition of human colon cancer.
Stehr AM, Wang G, Demmler R, Stemmler MP, Krug J, Tripal P, Schmid B, Geppert CI, Hartmann A, Muñoz LE, Schoen J, Völkl S, Merkel S, Becker C, Schett G, Grützmann R, Naschberger E, Herrmann M, Stürzl M. Stehr AM, et al. Among authors: stemmler mp. J Pathol. 2022 Apr;256(4):455-467. doi: 10.1002/path.5860. Epub 2022 Feb 15. J Pathol. 2022. PMID: 34939675
Editorial: Translational Insights Into Pancreatic Ductal Adenocarcinoma.
Bijlsma MF, Bailey PJ, Stemmler MP. Bijlsma MF, et al. Among authors: stemmler mp. Front Cell Dev Biol. 2022 Apr 1;10:875836. doi: 10.3389/fcell.2022.875836. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35433705 Free PMC article. No abstract available.
61 results