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Metabolite signatures associated with microRNA miR-143-3p serve as drivers of poor lung function trajectories in childhood asthma.
Mendez KM, Begum S, Tiwari A, Sharma R, Chen Q, Kelly RS, Prince N, Huang M, Kachroo P, Chu SH, Chen Y, Lee-Sarwar K, Broadhurst DI, Reinke SN, Gerszten R, Clish C, Avila L, Celedón JC, Wheelock CE, Weiss ST, McGeachie M, Lasky-Su JA. Mendez KM, et al. Among authors: broadhurst di. EBioMedicine. 2024 Apr;102:105025. doi: 10.1016/j.ebiom.2024.105025. Epub 2024 Mar 7. EBioMedicine. 2024. PMID: 38458111 Free PMC article.
Lipopolysaccharide-induced interferon response networks at birth are predictive of severe viral lower respiratory infections in the first year of life.
Read JF, Serralha M, Mok D, Holt BJ, Cruickshank M, Karpievitch YV, Broadhurst DI, Sly PD, Strickland DH, Reinke SN, Holt PG, Bosco A. Read JF, et al. Among authors: broadhurst di. Front Immunol. 2022 Aug 5;13:876654. doi: 10.3389/fimmu.2022.876654. eCollection 2022. Front Immunol. 2022. PMID: 35990635 Free PMC article.
Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study.
Reinke SN, Naz S, Chaleckis R, Gallart-Ayala H, Kolmert J, Kermani NZ, Tiotiu A, Broadhurst DI, Lundqvist A, Olsson H, Ström M, Wheelock ÅM, Gómez C, Ericsson M, Sousa AR, Riley JH, Bates S, Scholfield J, Loza M, Baribaud F, Bakke PS, Caruso M, Chanez P, Fowler SJ, Geiser T, Howarth P, Horváth I, Krug N, Montuschi P, Behndig A, Singer F, Musial J, Shaw DE, Dahlén B, Hu S, Lasky-Su J, Sterk PJ, Chung KF, Djukanovic R, Dahlén SE, Adcock IM, Wheelock CE; U-BIOPRED Study Group. Reinke SN, et al. Among authors: broadhurst di. Eur Respir J. 2022 Jun 30;59(6):2101733. doi: 10.1183/13993003.01733-2021. Print 2022 Jun. Eur Respir J. 2022. PMID: 34824054 Free PMC article.
Kynurenic acid may underlie sex-specific immune responses to COVID-19.
Cai Y, Kim DJ, Takahashi T, Broadhurst DI, Yan H, Ma S, Rattray NJW, Casanovas-Massana A, Israelow B, Klein J, Lucas C, Mao T, Moore AJ, Muenker MC, Oh JE, Silva J, Wong P; Yale IMPACT Research team; Ko AI, Khan SA, Iwasaki A, Johnson CH. Cai Y, et al. Among authors: broadhurst di. Sci Signal. 2021 Jul 6;14(690):eabf8483. doi: 10.1126/scisignal.abf8483. Sci Signal. 2021. PMID: 34230210 Free PMC article.
Kynurenic acid underlies sex-specific immune responses to COVID-19.
Cai Y, Kim DJ, Takahashi T, Broadhurst DI, Ma S, Rattray NJW, Casanovas-Massana A, Israelow B, Klein J, Lucas C, Mao T, Moore AJ, Muenker MC, Oh J, Silva J, Wong P; Yale IMPACT Research team; Ko AI, Khan SA, Iwasaki A, Johnson CH. Cai Y, et al. Among authors: broadhurst di. medRxiv [Preprint]. 2020 Sep 8:2020.09.06.20189159. doi: 10.1101/2020.09.06.20189159. medRxiv. 2020. PMID: 32935119 Free PMC article. Updated. Preprint.
39 results