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Long-read sequencing for fast and robust identification of correct genome-edited alleles: PCR-based and Cas9 capture methods.
McCabe CV, Price PD, Codner GF, Allan AJ, Caulder A, Christou S, Loeffler J, Mackenzie M, Malzer E, Mianné J, Nowicki KJ, O'Neill EJ, Pike FJ, Hutchison M, Petit-Demoulière B, Stewart ME, Gates H, Wells S, Sanderson ND, Teboul L. McCabe CV, et al. Among authors: codner gf. PLoS Genet. 2024 Mar 8;20(3):e1011187. doi: 10.1371/journal.pgen.1011187. eCollection 2024 Mar. PLoS Genet. 2024. PMID: 38457464 Free PMC article.
Application of long single-stranded DNA donors in genome editing: generation and validation of mouse mutants.
Codner GF, Mianné J, Caulder A, Loeffler J, Fell R, King R, Allan AJ, Mackenzie M, Pike FJ, McCabe CV, Christou S, Joynson S, Hutchison M, Stewart ME, Kumar S, Simon MM, Agius L, Anstee QM, Volynski KE, Kullmann DM, Wells S, Teboul L. Codner GF, et al. BMC Biol. 2018 Jun 21;16(1):70. doi: 10.1186/s12915-018-0530-7. BMC Biol. 2018. PMID: 29925374 Free PMC article.
Screening and validation of genome-edited animals.
Bunton-Stasyshyn RK, Codner GF, Teboul L. Bunton-Stasyshyn RK, et al. Among authors: codner gf. Lab Anim. 2022 Feb;56(1):69-82. doi: 10.1177/00236772211016922. Epub 2021 Jul 1. Lab Anim. 2022. PMID: 34192966 Free PMC article.
Genotyping Genome-Edited Founders and Subsequent Generation.
Mackenzie M, Fower A, Allan AJ, Codner GF, Bunton-Stasyshyn RK, Teboul L. Mackenzie M, et al. Among authors: codner gf. Methods Mol Biol. 2023;2631:103-134. doi: 10.1007/978-1-0716-2990-1_4. Methods Mol Biol. 2023. PMID: 36995665
Microhomologies are prevalent at Cas9-induced larger deletions.
Owens DDG, Caulder A, Frontera V, Harman JR, Allan AJ, Bucakci A, Greder L, Codner GF, Hublitz P, McHugh PJ, Teboul L, de Bruijn MFTR. Owens DDG, et al. Among authors: codner gf. Nucleic Acids Res. 2019 Aug 22;47(14):7402-7417. doi: 10.1093/nar/gkz459. Nucleic Acids Res. 2019. PMID: 31127293 Free PMC article.
A resource of targeted mutant mouse lines for 5,061 genes.
Birling MC, Yoshiki A, Adams DJ, Ayabe S, Beaudet AL, Bottomley J, Bradley A, Brown SDM, Bürger A, Bushell W, Chiani F, Chin HG, Christou S, Codner GF, DeMayo FJ, Dickinson ME, Doe B, Donahue LR, Fray MD, Gambadoro A, Gao X, Gertsenstein M, Gomez-Segura A, Goodwin LO, Heaney JD, Hérault Y, de Angelis MH, Jiang ST, Justice MJ, Kasparek P, King RE, Kühn R, Lee H, Lee YJ, Liu Z, Lloyd KCK, Lorenzo I, Mallon AM, McKerlie C, Meehan TF, Fuentes VM, Newman S, Nutter LMJ, Oh GT, Pavlovic G, Ramirez-Solis R, Rosen B, Ryder EJ, Santos LA, Schick J, Seavitt JR, Sedlacek R, Seisenberger C, Seong JK, Skarnes WC, Sorg T, Steel KP, Tamura M, Tocchini-Valentini GP, Wang CL, Wardle-Jones H, Wattenhofer-Donzé M, Wells S, Wiles MV, Willis BJ, Wood JA, Wurst W, Xu Y; International Mouse Phenotyping Consortium (IMPC); Teboul L, Murray SA. Birling MC, et al. Among authors: codner gf. Nat Genet. 2021 Apr;53(4):416-419. doi: 10.1038/s41588-021-00825-y. Nat Genet. 2021. PMID: 33833456 Free PMC article.
34 results