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Molecular hybridization: a powerful tool for multitarget drug discovery.
de Sena Murteira Pinheiro P, Franco LS, Montagnoli TL, Fraga CAM. de Sena Murteira Pinheiro P, et al. Expert Opin Drug Discov. 2024 Apr;19(4):451-470. doi: 10.1080/17460441.2024.2322990. Epub 2024 Mar 8. Expert Opin Drug Discov. 2024. PMID: 38456452 Review.
Design, Synthesis and Pharmacological Evaluation of Novel Conformationally Restricted N-arylpiperazine Derivatives Characterized as D2/D3 Receptor Ligands, Candidates for the Treatment of Neurodegenerative Diseases.
da Silva Cunha TT, Silva RR, Rodrigues DA, de Sena Murteira Pinheiro P, Kronenberger T, Sant'Anna CMR, Noël F, Fraga CAM. da Silva Cunha TT, et al. Among authors: de sena murteira pinheiro p. Biomolecules. 2022 Aug 12;12(8):1112. doi: 10.3390/biom12081112. Biomolecules. 2022. PMID: 36009006 Free PMC article.
Investigating the Molecular Basis for the Selective Inhibition of Aldehyde Dehydrogenase 2 by the Isoflavonoid Daidzin.
da Silva Cunha TT, de Souza FR, de Sena Murteira Pinheiro P, de Sant'Anna CMR, Noël F, Costa França TC, Manssour Fraga CA. da Silva Cunha TT, et al. Among authors: de sena murteira pinheiro p. CNS Neurol Disord Drug Targets. 2020;19(6):437-447. doi: 10.2174/1871527319999200817153150. CNS Neurol Disord Drug Targets. 2020. PMID: 32811404
Turning Donepezil into a Multi-Target-Directed Ligand through a Merging Strategy.
Perone R, Albertini C, Uliassi E, Di Pietri F, de Sena Murteira Pinheiro P, Petralla S, Rizzardi N, Fato R, Pulkrabkova L, Soukup O, Tramarin A, Bartolini M, Bolognesi ML. Perone R, et al. Among authors: de sena murteira pinheiro p. ChemMedChem. 2021 Jan 8;16(1):187-198. doi: 10.1002/cmdc.202000484. Epub 2020 Aug 31. ChemMedChem. 2021. PMID: 32716144