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21 results

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Page 1
Autophagy Contributes to Homeostasis in Esophageal Epithelium Where High Autophagic Vesicle Level Marks Basal Cells With Limited Proliferation and Enhanced Self-Renewal Potential.
Klochkova A, Karami AL, Fuller AD, Parham LR, Panchani SR, Natarajan S, Jackson JL, Mu A, Tan Y, Cai KQ, Klein-Szanto AJ, Muir AB, Tétreault MP, Graña X, Hamilton KE, Whelan KA. Klochkova A, et al. Among authors: parham lr. Cell Mol Gastroenterol Hepatol. 2024 Mar 5;18(1):15-40. doi: 10.1016/j.jcmgh.2024.02.018. Online ahead of print. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38452871 Free PMC article.
RNA regulons are essential in intestinal homeostasis.
Parham LR, Williams PA, Chatterji P, Whelan KA, Hamilton KE. Parham LR, et al. Am J Physiol Gastrointest Liver Physiol. 2019 Jan 1;316(1):G197-G204. doi: 10.1152/ajpgi.00403.2017. Epub 2018 Dec 6. Am J Physiol Gastrointest Liver Physiol. 2019. PMID: 30520692 Free PMC article. Review.
Autophagic state prospectively identifies facultative stem cells in the intestinal epithelium.
Johnson NM, Parham LR, Na J, Monaghan KE, Kolev HM, Klochkova A, Kim MS, Danan CH, Cramer Z, Simon LA, Naughton KE, Adams-Tzivelekidis S, Tian Y, Williams PA, Leu NA, Sidoli S, Whelan KA, Li N, Lengner CJ, Hamilton KE. Johnson NM, et al. Among authors: parham lr. EMBO Rep. 2022 Nov 7;23(11):e55209. doi: 10.15252/embr.202255209. Epub 2022 Sep 19. EMBO Rep. 2022. PMID: 36120829 Free PMC article.
Autophagy contributes to homeostasis in esophageal epithelium where high autophagic vesicle content marks basal cells with limited proliferation and enhanced self-renewal potential.
Klochkova A, Karami AL, Fuller AD, Parham LR, Panchani SR, Natarajan S, Jackson JL, Mu A, Tan Y, Cai KQ, Klein-Szanto AJ, Muir AB, Tétreault MP, Hamilton KE, Whelan KA. Klochkova A, et al. Among authors: parham lr. bioRxiv [Preprint]. 2023 Sep 22:2023.09.20.558614. doi: 10.1101/2023.09.20.558614. bioRxiv. 2023. PMID: 37781581 Free PMC article. Updated. Preprint.
IGF2BP1/IMP1 Deletion Enhances a Facultative Stem Cell State via Regulation of MAP1LC3B.
Parham LR, Williams PA, Katada K, Nettleford SK, Chatterji P, Acheampong KK, Danan CH, Ma X, Simon LA, Naughton KE, Mizuno R, Karakasheva T, McMillan EA, Whelan KA, Brady DC, Shaffer SM, Hamilton KE. Parham LR, et al. Cell Mol Gastroenterol Hepatol. 2024;17(3):439-451. doi: 10.1016/j.jcmgh.2023.12.001. Epub 2023 Dec 9. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38081361 Free PMC article.
Intestinal epithelial autophagy is required for the regenerative benefit of calorie restriction.
Williams PA, Naughton KE, Simon LA, Soto GE, Parham LR, Ma X, Danan CH, Hu W, Friedman ES, McMillan EA, Mehta H, Stoltz MA, Ocaña JS, Zackular JP, Bittinger K, Whelan KA, Karakasheva TA, Hamilton KE. Williams PA, et al. Among authors: parham lr. Am J Physiol Gastrointest Liver Physiol. 2023 May 1;324(5):G354-G368. doi: 10.1152/ajpgi.00248.2022. Epub 2023 Feb 28. Am J Physiol Gastrointest Liver Physiol. 2023. PMID: 36852920 Free PMC article.
Posttranscriptional regulation of colonic epithelial repair by RNA binding protein IMP1/IGF2BP1.
Chatterji P, Williams PA, Whelan KA, Samper FC, Andres SF, Simon LA, Parham LR, Mizuno R, Lundsmith ET, Lee DS, Liang S, Wijeratne HS, Marti S, Chau L, Giroux V, Wilkins BJ, Wu GD, Shah P, Tartaglia GG, Hamilton KE. Chatterji P, et al. Among authors: parham lr. EMBO Rep. 2019 Jun;20(6):e47074. doi: 10.15252/embr.201847074. Epub 2019 May 6. EMBO Rep. 2019. PMID: 31061170 Free PMC article.
Spatial transcriptomics add a new dimension to our understanding of the gut.
Danan CH, Katada K, Parham LR, Hamilton KE. Danan CH, et al. Among authors: parham lr. Am J Physiol Gastrointest Liver Physiol. 2023 Feb 1;324(2):G91-G98. doi: 10.1152/ajpgi.00191.2022. Epub 2022 Dec 6. Am J Physiol Gastrointest Liver Physiol. 2023. PMID: 36472345 Free PMC article. Review.
Intestinal transit amplifying cells require METTL3 for growth factor signaling, KRAS expression, and cell survival.
Danan CH, Naughton KE, Hayer KE, Vellappan S, McMillan EA, Zhou Y, Matsuda R, Nettleford SK, Katada K, Parham LR, Ma X, Chowdhury A, Wilkins BJ, Shah P, Weitzman MD, Hamilton KE. Danan CH, et al. Among authors: parham lr. bioRxiv [Preprint]. 2023 Apr 21:2023.04.06.535853. doi: 10.1101/2023.04.06.535853. bioRxiv. 2023. PMID: 37066277 Free PMC article. Updated. Preprint.
21 results