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Page 1
Integrated data from intravital imaging and HPLC-MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats.
Hassan R, Gerdemann A, Cramer B, Hobloss Z, Myllys M, González D, Albrecht W, Veerkamp J, Friebel A, Hoehme S, Esselen M, Degen GH, Humpf HU, Hengstler JG, Ghallab A. Hassan R, et al. Among authors: albrecht w. Arch Toxicol. 2024 Apr;98(4):1081-1093. doi: 10.1007/s00204-024-03688-4. Epub 2024 Mar 4. Arch Toxicol. 2024. PMID: 38436695
Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity.
Hassan R, Friebel A, Brackhagen L, Hobloss Z, Myllys M, González D, Albrecht W, Mohammed ESI, Seddek AL, Marchan R, Cadenas C, Cramer B, Humpf HU, Hartl L, Simbrunner B, Reiberger T, Trauner M, Hoehme S, Degen GH, Hengstler JG, Ghallab A. Hassan R, et al. Among authors: albrecht w. Arch Toxicol. 2022 Nov;96(11):2967-2981. doi: 10.1007/s00204-022-03361-8. Epub 2022 Aug 13. Arch Toxicol. 2022. PMID: 35962801 Free PMC article.
Comparing in vitro human liver models to in vivo human liver using RNA-Seq.
Gupta R, Schrooders Y, Hauser D, van Herwijnen M, Albrecht W, Ter Braak B, Brecklinghaus T, Castell JV, Elenschneider L, Escher S, Guye P, Hengstler JG, Ghallab A, Hansen T, Leist M, Maclennan R, Moritz W, Tolosa L, Tricot T, Verfaillie C, Walker P, van de Water B, Kleinjans J, Caiment F. Gupta R, et al. Among authors: albrecht w. Arch Toxicol. 2021 Feb;95(2):573-589. doi: 10.1007/s00204-020-02937-6. Epub 2020 Oct 27. Arch Toxicol. 2021. PMID: 33106934 Free PMC article.
Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis.
Ghallab A, González D, Strängberg E, Hofmann U, Myllys M, Hassan R, Hobloss Z, Brackhagen L, Begher-Tibbe B, Duda JC, Drenda C, Kappenberg F, Reinders J, Friebel A, Vucur M, Turajski M, Seddek AL, Abbas T, Abdelmageed N, Morad SAF, Morad W, Hamdy A, Albrecht W, Kittana N, Assali M, Vartak N, van Thriel C, Sous A, Nell P, Villar-Fernandez M, Cadenas C, Genc E, Marchan R, Luedde T, Åkerblad P, Mattsson J, Marschall HU, Hoehme S, Stirnimann G, Schwab M, Boor P, Amann K, Schmitz J, Bräsen JH, Rahnenführer J, Edlund K, Karpen SJ, Simbrunner B, Reiberger T, Mandorfer M, Trauner M, Dawson PA, Lindström E, Hengstler JG. Ghallab A, et al. Among authors: albrecht w. J Hepatol. 2024 Feb;80(2):268-281. doi: 10.1016/j.jhep.2023.10.035. Epub 2023 Nov 7. J Hepatol. 2024. PMID: 37939855 Free PMC article.
Relevance of the incubation period in cytotoxicity testing with primary human hepatocytes.
Gu X, Albrecht W, Edlund K, Kappenberg F, Rahnenführer J, Leist M, Moritz W, Godoy P, Cadenas C, Marchan R, Brecklinghaus T, Pardo LT, Castell JV, Gardner I, Han B, Hengstler JG, Stoeber R. Gu X, et al. Among authors: albrecht w. Arch Toxicol. 2018 Dec;92(12):3505-3515. doi: 10.1007/s00204-018-2302-0. Epub 2018 Oct 13. Arch Toxicol. 2018. PMID: 30317417
Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations.
Albrecht W, Kappenberg F, Brecklinghaus T, Stoeber R, Marchan R, Zhang M, Ebbert K, Kirschner H, Grinberg M, Leist M, Moritz W, Cadenas C, Ghallab A, Reinders J, Vartak N, van Thriel C, Golka K, Tolosa L, Castell JV, Damm G, Seehofer D, Lampen A, Braeuning A, Buhrke T, Behr AC, Oberemm A, Gu X, Kittana N, van de Water B, Kreiling R, Fayyaz S, van Aerts L, Smedsrød B, Ellinger-Ziegelbauer H, Steger-Hartmann T, Gundert-Remy U, Zeigerer A, Ullrich A, Runge D, Lee SML, Schiergens TS, Kuepfer L, Aguayo-Orozco A, Sachinidis A, Edlund K, Gardner I, Rahnenführer J, Hengstler JG. Albrecht W, et al. Arch Toxicol. 2019 Jun;93(6):1609-1637. doi: 10.1007/s00204-019-02492-9. Epub 2019 Jun 27. Arch Toxicol. 2019. PMID: 31250071
Handling deviating control values in concentration-response curves.
Kappenberg F, Brecklinghaus T, Albrecht W, Blum J, van der Wurp C, Leist M, Hengstler JG, Rahnenführer J. Kappenberg F, et al. Among authors: albrecht w. Arch Toxicol. 2020 Nov;94(11):3787-3798. doi: 10.1007/s00204-020-02913-0. Epub 2020 Sep 23. Arch Toxicol. 2020. PMID: 32965549 Free PMC article.
279 results