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Homozygous ALS-linked mutations in TARDBP/TDP-43 lead to hypoactivity and synaptic abnormalities in human iPSC-derived motor neurons.
iScience. 2024 Feb 9;27(3):109166. doi: 10.1016/j.isci.2024.109166. eCollection 2024 Mar 15.
iScience. 2024.
PMID: 38433895
Free PMC article.
An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids.
Castellanos-Montiel MJ, Chaineau M, Franco-Flores AK, Haghi G, Carrillo-Valenzuela D, Reintsch WE, Chen CX, Durcan TM.
Castellanos-Montiel MJ, et al. Among authors: franco flores ak.
Cells. 2023 Feb 8;12(4):545. doi: 10.3390/cells12040545.
Cells. 2023.
PMID: 36831212
Free PMC article.
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Rapid Generation of Ventral Spinal Cord-like Astrocytes from Human iPSCs for Modeling Non-Cell Autonomous Mechanisms of Lower Motor Neuron Disease.
Soubannier V, Chaineau M, Gursu L, Haghi G, Franco Flores AK, Rouleau G, Durcan TM, Stifani S.
Soubannier V, et al. Among authors: franco flores ak.
Cells. 2022 Jan 24;11(3):399. doi: 10.3390/cells11030399.
Cells. 2022.
PMID: 35159209
Free PMC article.
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A streamlined CRISPR workflow to introduce mutations and generate isogenic iPSCs for modeling amyotrophic lateral sclerosis.
Deneault E, Chaineau M, Nicouleau M, Castellanos Montiel MJ, Franco Flores AK, Haghi G, Chen CX, Abdian N, Shlaifer I, Beitel LK, Durcan TM.
Deneault E, et al. Among authors: franco flores ak.
Methods. 2022 Jul;203:297-310. doi: 10.1016/j.ymeth.2021.09.002. Epub 2021 Sep 6.
Methods. 2022.
PMID: 34500068
Free article.
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