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CRISPR/Cas9 screenings unearth protein arginine methyltransferase 7 as a novel essential gene in prostate cancer metastasis.
Rodrigo-Faus M, Vincelle-Nieto A, Vidal N, Puente J, Saiz-Pardo M, Lopez-Garcia A, Mendiburu-Eliçabe M, Palao N, Baquero C, Linzoain-Agos P, Cuesta AM, Qu HQ, Hakonarson H, Musteanu M, Reyes-Palomares A, Porras A, Bragado P, Gutierrez-Uzquiza A. Rodrigo-Faus M, et al. Among authors: porras a. Cancer Lett. 2024 Apr 28;588:216776. doi: 10.1016/j.canlet.2024.216776. Epub 2024 Mar 2. Cancer Lett. 2024. PMID: 38432581 Free article.
Met signaling in cardiomyocytes is required for normal cardiac function in adult mice.
Arechederra M, Carmona R, González-Nuñez M, Gutiérrez-Uzquiza A, Bragado P, Cruz-González I, Cano E, Guerrero C, Sánchez A, López-Novoa JM, Schneider MD, Maina F, Muñoz-Chápuli R, Porras A. Arechederra M, et al. Among authors: porras a. Biochim Biophys Acta. 2013 Dec;1832(12):2204-15. doi: 10.1016/j.bbadis.2013.08.008. Epub 2013 Aug 28. Biochim Biophys Acta. 2013. PMID: 23994610 Free article.
p38 MAPK down-regulates fibulin 3 expression through methylation of gene regulatory sequences: role in migration and invasion.
Arechederra M, Priego N, Vázquez-Carballo A, Sequera C, Gutiérrez-Uzquiza Á, Cerezo-Guisado MI, Ortiz-Rivero S, Roncero C, Cuenda A, Guerrero C, Porras A. Arechederra M, et al. Among authors: porras a. J Biol Chem. 2015 Feb 13;290(7):4383-97. doi: 10.1074/jbc.M114.582239. Epub 2014 Dec 29. J Biol Chem. 2015. PMID: 25548290 Free PMC article.
C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mechanisms.
Priego N, Arechederra M, Sequera C, Bragado P, Vázquez-Carballo A, Gutiérrez-Uzquiza Á, Martín-Granado V, Ventura JJ, Kazanietz MG, Guerrero C, Porras A. Priego N, et al. Among authors: porras a. Oncotarget. 2016 Jul 19;7(29):45060-45078. doi: 10.18632/oncotarget.9911. Oncotarget. 2016. PMID: 27286263 Free PMC article.
267 results