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ASOs are an effective treatment for disease-associated oligodendrocyte signatures in premanifest and symptomatic SCA3 mice.
Mol Ther. 2024 May 1;32(5):1359-1372. doi: 10.1016/j.ymthe.2024.02.033. Epub 2024 Feb 29.
Mol Ther. 2024.
PMID: 38429929
Disease-associated oligodendrocyte signatures are spatiotemporally dysregulated in spinocerebellar ataxia type 3.
Schuster KH, DiFranco DM, Putka AF, Mato JP, Jarrah SI, Stec NR, Sundararajan VO, McLoughlin HS.
Schuster KH, et al. Among authors: jarrah si.
Front Neurosci. 2023 Feb 15;17:1118429. doi: 10.3389/fnins.2023.1118429. eCollection 2023.
Front Neurosci. 2023.
PMID: 36875652
Free PMC article.
Item in Clipboard
Blood neurofilament light chain levels are associated with disease progression in a transgenic SCA3 mouse model.
Mengel D, Wellik IG, Schuster KH, Jarrah SI, Wacker M, Ashraf NS, Öz G, Synofzik M, do Carmo Costa M, McLoughlin HS.
Mengel D, et al. Among authors: jarrah si.
bioRxiv [Preprint]. 2023 Mar 1:2023.02.28.530463. doi: 10.1101/2023.02.28.530463.
bioRxiv. 2023.
PMID: 36909535
Free PMC article.
Updated.
Preprint.
Item in Clipboard
Blood levels of neurofilament light are associated with disease progression in a mouse model of spinocerebellar ataxia type 3.
Mengel D, Wellik IG, Schuster KH, Jarrah SI, Wacker M, Ashraf NS, Öz G, Synofzik M, Costa MDC, McLoughlin HS.
Mengel D, et al. Among authors: jarrah si.
Dis Model Mech. 2023 Sep 1;16(9):dmm050144. doi: 10.1242/dmm.050144. Epub 2023 Sep 4.
Dis Model Mech. 2023.
PMID: 37664882
Free PMC article.
Item in Clipboard
Purkinje-Enriched snRNA-seq in SCA7 Cerebellum Reveals Zebrin Identity Loss as a Central Feature of Polyglutamine Ataxias.
Bartelt LC, Switonski PM, Adamek G, Carvalho J, Duvick LA, Jarrah SI, McLoughlin HS, Scoles DR, Pulst SM, Orr HT, Hull C, Lowe CB, La Spada AR.
Bartelt LC, et al. Among authors: jarrah si.
bioRxiv [Preprint]. 2023 May 11:2023.03.19.533345. doi: 10.1101/2023.03.19.533345.
bioRxiv. 2023.
PMID: 37214832
Free PMC article.
Preprint.
Item in Clipboard
Microfluidic 'brain-on chip' systems to supplement neurological practice: development, applications and considerations.
Jarrah R, Nathani KR, Bhandarkar S, Ezeudu CS, Nguyen RT, Amare A, Aljameey UA, Jarrah SI, Bhandarkar AR, Fiani B.
Jarrah R, et al. Among authors: jarrah si.
Regen Med. 2023 May;18(5):413-423. doi: 10.2217/rme-2022-0212. Epub 2023 Apr 26.
Regen Med. 2023.
PMID: 37125510
Review.
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