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Modeling T cell temporal response to cancer immunotherapy rationalizes development of combinatorial treatment protocols.
Barboy O, Bercovich A, Li H, Eyal-Lubling Y, Yalin A, Shapir Itai Y, Abadie K, Zada M, David E, Shlomi-Loubaton S, Katzenelenbogen Y, Jaitin DA, Gur C, Yofe I, Feferman T, Cohen M, Dahan R, Newell EW, Lifshitz A, Tanay A, Amit I. Barboy O, et al. Among authors: tanay a. Nat Cancer. 2024 May;5(5):742-759. doi: 10.1038/s43018-024-00734-z. Epub 2024 Mar 1. Nat Cancer. 2024. PMID: 38429414
The interaction of CD4+ helper T cells with dendritic cells shapes the tumor microenvironment and immune checkpoint blockade response.
Cohen M, Giladi A, Barboy O, Hamon P, Li B, Zada M, Gurevich-Shapiro A, Beccaria CG, David E, Maier BB, Buckup M, Kamer I, Deczkowska A, Le Berichel J, Bar J, Iannacone M, Tanay A, Merad M, Amit I. Cohen M, et al. Among authors: tanay a. Nat Cancer. 2022 Mar;3(3):303-317. doi: 10.1038/s43018-022-00338-5. Epub 2022 Mar 3. Nat Cancer. 2022. PMID: 35241835
Dissecting cellular crosstalk by sequencing physically interacting cells.
Giladi A, Cohen M, Medaglia C, Baran Y, Li B, Zada M, Bost P, Blecher-Gonen R, Salame TM, Mayer JU, David E, Ronchese F, Tanay A, Amit I. Giladi A, et al. Among authors: tanay a. Nat Biotechnol. 2020 May;38(5):629-637. doi: 10.1038/s41587-020-0442-2. Epub 2020 Mar 9. Nat Biotechnol. 2020. PMID: 32152598
Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.
Li H, van der Leun AM, Yofe I, Lubling Y, Gelbard-Solodkin D, van Akkooi ACJ, van den Braber M, Rozeman EA, Haanen JBAG, Blank CU, Horlings HM, David E, Baran Y, Bercovich A, Lifshitz A, Schumacher TN, Tanay A, Amit I. Li H, et al. Among authors: tanay a. Cell. 2019 Feb 7;176(4):775-789.e18. doi: 10.1016/j.cell.2018.11.043. Epub 2018 Dec 27. Cell. 2019. PMID: 30595452 Free PMC article.
Single-cell analysis of regions of interest (SCARI) using a photosensitive tag.
van der Leun AM, Hoekstra ME, Reinalda L, Scheele CLGJ, Toebes M, van de Graaff MJ, Chen LYY, Li H, Bercovich A, Lubling Y, David E, Thommen DS, Tanay A, van Rheenen J, Amit I, van Kasteren SI, Schumacher TN. van der Leun AM, et al. Among authors: tanay a. Nat Chem Biol. 2021 Nov;17(11):1139-1147. doi: 10.1038/s41589-021-00839-x. Epub 2021 Sep 9. Nat Chem Biol. 2021. PMID: 34504322 Free PMC article.
Deterministic direct reprogramming of somatic cells to pluripotency.
Rais Y, Zviran A, Geula S, Gafni O, Chomsky E, Viukov S, Mansour AA, Caspi I, Krupalnik V, Zerbib M, Maza I, Mor N, Baran D, Weinberger L, Jaitin DA, Lara-Astiaso D, Blecher-Gonen R, Shipony Z, Mukamel Z, Hagai T, Gilad S, Amann-Zalcenstein D, Tanay A, Amit I, Novershtern N, Hanna JH. Rais Y, et al. Among authors: tanay a. Nature. 2013 Oct 3;502(7469):65-70. doi: 10.1038/nature12587. Epub 2013 Sep 18. Nature. 2013. PMID: 24048479
165 results