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G2019S selective LRRK2 kinase inhibitor abrogates mitochondrial DNA damage.
Pena N, Richbourg T, Gonzalez-Hunt CP, Qi R, Wren P, Barlow C, Shanks NF, Carlisle HJ, Sanders LH. Pena N, et al. Among authors: barlow c. NPJ Parkinsons Dis. 2024 Mar 1;10(1):49. doi: 10.1038/s41531-024-00660-y. NPJ Parkinsons Dis. 2024. PMID: 38429321 Free PMC article.
A Phase 1 First-in-Human Single-Ascending-Dose Trial With ESB1609, a Selective Agonist to the Sphingosine-1-Phosphate Receptor 5.
France NP, Rubino C, Safir MC, Maurer M, Duong T, Singamsetty D, Abd-Elaziz K, Chou T, Sankaranarayanan S, Ettema M, Cosford R, Dogterom P, Liu E, Barlow C. France NP, et al. Among authors: barlow c. Clin Pharmacol Drug Dev. 2023 Jun;12(6):625-638. doi: 10.1002/cpdd.1256. Epub 2023 May 16. Clin Pharmacol Drug Dev. 2023. PMID: 37191222 Clinical Trial.
BCI-838, an orally active mGluR2/3 receptor antagonist pro-drug, rescues learning behavior deficits in the PS19 MAPTP301S mouse model of tauopathy.
Perez-Garcia G, Bicak M, Haure-Mirande JV, Perez GM, Otero-Pagan A, Gama Sosa MA, De Gasperi R, Sano M, Barlow C, Gage FH, Readhead B, Ehrlich ME, Gandy S, Elder GA. Perez-Garcia G, et al. Among authors: barlow c. Neurosci Lett. 2023 Feb 16;797:137080. doi: 10.1016/j.neulet.2023.137080. Epub 2023 Jan 16. Neurosci Lett. 2023. PMID: 36657633 Free PMC article.
A defined diet for pre-adult Drosophila melanogaster.
Martelli F, Quig A, Mele S, Lin J, Fulton TL, Wansbrough M, Barlow CK, Schittenhelm RB, Johnson TK, Piper MDW. Martelli F, et al. Among authors: barlow ck. Sci Rep. 2024 Mar 23;14(1):6974. doi: 10.1038/s41598-024-57681-z. Sci Rep. 2024. PMID: 38521863 Free PMC article.
641 results