Mutchler SM - Search Results

1

PIEZO1 is a distal nephron mechanosensor and is required for flow-induced K+ secretion.

Carrisoza-Gaytan R, Mutchler SM, Carattino F, Soong J, Dalghi MG, Wu P, Wang W, Apodaca G, Satlin LM, Kleyman TR. Carrisoza-Gaytan R, et al. Among authors: mutchler sm. J Clin Invest. 2024 Mar 1;134(5):e174806. doi: 10.1172/JCI174806. J Clin Invest. 2024. PMID: 38426496 Free PMC article.

2

Excess dietary sodium partially restores salt and water homeostasis caused by loss of the endoplasmic reticulum molecular chaperone, GRP170, in the mouse nephron.

Porter A, Vorndran HE, Marciszyn A, Mutchler SM, Subramanya AR, Kleyman TR, Hendershot LM, Brodsky JL, Buck TM. Porter A, et al. Among authors: mutchler sm. bioRxiv [Preprint]. 2024 Jan 14:2024.01.13.575426. doi: 10.1101/2024.01.13.575426. bioRxiv. 2024. PMID: 38260467 Free PMC article. Preprint.

3

Kcnma1 alternative splicing in mouse kidney: regulation during development and by dietary K⁺ intake.

Whelan SCM, Mutchler SM, Han A, Priestley C, Satlin LM, Kleyman TR, Shi S. Whelan SCM, et al. Among authors: mutchler sm. Am J Physiol Renal Physiol. 2024 May 23. doi: 10.1152/ajprenal.00100.2024. Online ahead of print. Am J Physiol Renal Physiol. 2024. PMID: 38779757

4

Role of paraoxonase 3 in regulating ENaC-mediated Na⁺ transport in the distal nephron.

Mutchler SM, Whelan SCM, Marciszyn A, Chen J, Kleyman TR, Shi S. Mutchler SM, et al. J Physiol. 2024 Feb;602(4):737-757. doi: 10.1113/JP285034. Epub 2024 Feb 12. J Physiol. 2024. PMID: 38345534

5

Dietary sodium alters aldosterone's effect on renal sodium transporter expression and distal convoluted tubule remodelling.

Mutchler SM, Hasan M, Murphy CP, Baty CJ, Boyd-Shiwarski C, Kirabo A, Kleyman TR. Mutchler SM, et al. J Physiol. 2024 Mar;602(5):967-987. doi: 10.1113/JP284041. Epub 2024 Jan 31. J Physiol. 2024. PMID: 38294810

6

Mineralocorticoid receptor-independent activation of ENaC in bile duct ligated mice.

Wang XP, Mutchler SM, Carrisoza-Gáytan R, Al-Bataineh M, Baty CJ, Vandevender A, Srinivasan P, Tan RJ, Jurczak MJ, Satlin LM, Kashlan OB. Wang XP, et al. Among authors: mutchler sm. bioRxiv [Preprint]. 2023 Sep 22:2023.09.19.558474. doi: 10.1101/2023.09.19.558474. bioRxiv. 2023. PMID: 37790468 Free PMC article. Preprint.

7

Mice lacking γENaC palmitoylation sites maintain benzamil-sensitive Na+ transport despite reduced channel activity.

Nickerson AJ, Mutchler SM, Sheng S, Cox NA, Ray EC, Kashlan OB, Carattino MD, Marciszyn AL, Winfrey A, Gingras S, Kirabo A, Hughey RP, Kleyman TR. Nickerson AJ, et al. Among authors: mutchler sm. JCI Insight. 2023 Nov 8;8(21):e172051. doi: 10.1172/jci.insight.172051. JCI Insight. 2023. PMID: 37707951 Free PMC article.

8

Validation of commercially available antibodies directed against subunits of the epithelial Na⁺ channel.

Mutchler SM, Shi S, Whelan SCM, Kleyman TR. Mutchler SM, et al. Physiol Rep. 2023 Jan;11(1):e15554. doi: 10.14814/phy2.15554. Physiol Rep. 2023. PMID: 36636010 Free PMC article.

9

Effects of amiloride on acetylcholine-dependent arterial vasodilation evolve over time in mice on a high salt diet.

Mutchler SM, Kleyman TR. Mutchler SM, et al. Physiol Rep. 2022 Apr;10(7):e15255. doi: 10.14814/phy2.15255. Physiol Rep. 2022. PMID: 35384364 Free PMC article.

10

The molecular chaperone GRP170 protects against ER stress and acute kidney injury in mice.

Porter AW, Nguyen DN, Clayton DR, Ruiz WG, Mutchler SM, Ray EC, Marciszyn AL, Nkashama LJ, Subramanya AR, Gingras S, Kleyman TR, Apodaca G, Hendershot LM, Brodsky JL, Buck TM. Porter AW, et al. Among authors: mutchler sm. JCI Insight. 2022 Mar 8;7(5):e151869. doi: 10.1172/jci.insight.151869. JCI Insight. 2022. PMID: 35104250 Free PMC article.

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