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Time-resolved role of P2X4 and P2X7 during CD8+ T cell activation.
Brock VJ, Lory NC, Möckl F, Birus M, Stähler T, Woelk LM, Jaeckstein M, Heeren J, Koch-Nolte F, Rissiek B, Mittrücker HW, Guse AH, Werner R, Diercks BP. Brock VJ, et al. Among authors: mockl f. Front Immunol. 2024 Feb 15;15:1258119. doi: 10.3389/fimmu.2024.1258119. eCollection 2024. Front Immunol. 2024. PMID: 38426095 Free PMC article.
Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca2+ signaling during T cell activation.
Gu F, Krüger A, Roggenkamp HG, Alpers R, Lodygin D, Jaquet V, Möckl F, Hernandez C LC, Winterberg K, Bauche A, Rosche A, Grasberger H, Kao JY, Schetelig D, Werner R, Schröder K, Carty M, Bowie AG, Huber S, Meier C, Mittrücker HW, Heeren J, Krause KH, Flügel A, Diercks BP, Guse AH. Gu F, et al. Among authors: mockl f. Sci Signal. 2021 Nov 16;14(709):eabe3800. doi: 10.1126/scisignal.abe3800. Epub 2021 Nov 16. Sci Signal. 2021. PMID: 34784249
HN1L/JPT2: A signaling protein that connects NAADP generation to Ca2+ microdomain formation.
Roggenkamp HG, Khansahib I, Hernandez C LC, Zhang Y, Lodygin D, Krüger A, Gu F, Möckl F, Löhndorf A, Wolters V, Woike D, Rosche A, Bauche A, Schetelig D, Werner R, Schlüter H, Failla AV, Meier C, Fliegert R, Walseth TF, Flügel A, Diercks BP, Guse AH. Roggenkamp HG, et al. Among authors: mockl f. Sci Signal. 2021 Mar 23;14(675):eabd5647. doi: 10.1126/scisignal.abd5647. Sci Signal. 2021. PMID: 33758062
High Metabolic Function and Resilience of NKG2A-Educated NK Cells.
Highton AJ, Diercks BP, Möckl F, Martrus G, Sauter J, Schmidt AH, Bunders MJ, Körner C, Guse AH, Altfeld M. Highton AJ, et al. Among authors: mockl f. Front Immunol. 2020 Sep 30;11:559576. doi: 10.3389/fimmu.2020.559576. eCollection 2020. Front Immunol. 2020. PMID: 33101277 Free PMC article.
Novel CaM-binding motif in its NudT9H domain contributes to temperature sensitivity of TRPM2.
Gattkowski E, Johnsen A, Bauche A, Möckl F, Kulow F, Garcia Alai M, Rutherford TJ, Fliegert R, Tidow H. Gattkowski E, et al. Among authors: mockl f. Biochim Biophys Acta Mol Cell Res. 2019 Jul;1866(7):1162-1170. doi: 10.1016/j.bbamcr.2018.12.010. Epub 2018 Dec 22. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 30584900 Free PMC article.