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Time-resolved role of P2X4 and P2X7 during CD8+ T cell activation.
Brock VJ, Lory NC, Möckl F, Birus M, Stähler T, Woelk LM, Jaeckstein M, Heeren J, Koch-Nolte F, Rissiek B, Mittrücker HW, Guse AH, Werner R, Diercks BP. Brock VJ, et al. Among authors: heeren j. Front Immunol. 2024 Feb 15;15:1258119. doi: 10.3389/fimmu.2024.1258119. eCollection 2024. Front Immunol. 2024. PMID: 38426095 Free PMC article.
CD38 downregulation modulates NAD+ and NADP(H) levels in thermogenic adipose tissues.
Benzi A, Sturla L, Heine M, Fischer AW, Spinelli S, Magnone M, Sociali G, Parodi A, Fenoglio D, Emionite L, Koch-Nolte F, Mittrücker HW, Guse AH, De Flora A, Zocchi E, Heeren J, Bruzzone S. Benzi A, et al. Among authors: heeren j. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Jan;1866(1):158819. doi: 10.1016/j.bbalip.2020.158819. Epub 2020 Sep 30. Biochim Biophys Acta Mol Cell Biol Lipids. 2021. PMID: 33010451
Nanoparticle-mediated targeting of autoantigen peptide to cross-presenting liver sinusoidal endothelial cells protects from CD8 T-cell-driven autoimmune cholangitis.
Carambia A, Gottwick C, Schwinge D, Stein S, Digigow R, Şeleci M, Mungalpara D, Heine M, Schuran FA, Corban C, Lohse AW, Schramm C, Heeren J, Herkel J. Carambia A, et al. Among authors: heeren j. Immunology. 2021 Apr;162(4):452-463. doi: 10.1111/imm.13298. Epub 2021 Jan 7. Immunology. 2021. PMID: 33346377 Free PMC article.
Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation.
Fischer AW, Jaeckstein MY, Gottschling K, Heine M, Sass F, Mangels N, Schlein C, Worthmann A, Bruns OT, Yuan Y, Zhu H, Chen O, Ittrich H, Nilsson SK, Stefanicka P, Ukropec J, Balaz M, Dong H, Sun W, Reimer R, Scheja L, Heeren J. Fischer AW, et al. Among authors: heeren j. Cell Metab. 2021 Mar 2;33(3):547-564.e7. doi: 10.1016/j.cmet.2020.12.001. Epub 2020 Dec 22. Cell Metab. 2021. PMID: 33357458 Free article.
Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution.
Schlein C, Fischer AW, Sass F, Worthmann A, Tödter K, Jaeckstein MY, Behrens J, Lynes MD, Kiebish MA, Narain NR, Bussberg V, Darkwah A, Jespersen NZ, Nielsen S, Scheele C, Schweizer M, Braren I, Bartelt A, Tseng YH, Heeren J, Scheja L. Schlein C, et al. Among authors: heeren j. Cell Rep. 2021 Jan 12;34(2):108624. doi: 10.1016/j.celrep.2020.108624. Cell Rep. 2021. PMID: 33440156 Free PMC article.
Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca2+ signaling during T cell activation.
Gu F, Krüger A, Roggenkamp HG, Alpers R, Lodygin D, Jaquet V, Möckl F, Hernandez C LC, Winterberg K, Bauche A, Rosche A, Grasberger H, Kao JY, Schetelig D, Werner R, Schröder K, Carty M, Bowie AG, Huber S, Meier C, Mittrücker HW, Heeren J, Krause KH, Flügel A, Diercks BP, Guse AH. Gu F, et al. Among authors: heeren j. Sci Signal. 2021 Nov 16;14(709):eabe3800. doi: 10.1126/scisignal.abe3800. Epub 2021 Nov 16. Sci Signal. 2021. PMID: 34784249
Role of CD38 in Adipose Tissue: Tuning Coenzyme Availability?
Benzi A, Grozio A, Spinelli S, Sturla L, Guse AH, De Flora A, Zocchi E, Heeren J, Bruzzone S. Benzi A, et al. Among authors: heeren j. Nutrients. 2021 Oct 23;13(11):3734. doi: 10.3390/nu13113734. Nutrients. 2021. PMID: 34835990 Free PMC article. Review.
236 results