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Dabrafenib Alters MDSC Differentiation and Function by Activation of GCN2.
Ciudad MT, Quevedo R, Lamorte S, Jin R, Nzirorera N, Koritzinsky M, McGaha TL. Ciudad MT, et al. Among authors: koritzinsky m. Cancer Res Commun. 2024 Mar 13;4(3):765-784. doi: 10.1158/2767-9764.CRC-23-0376. Cancer Res Commun. 2024. PMID: 38421883 Free PMC article.
The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic autoimmunity.
Ravishankar B, Liu H, Shinde R, Chaudhary K, Xiao W, Bradley J, Koritzinsky M, Madaio MP, McGaha TL. Ravishankar B, et al. Among authors: koritzinsky m. Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10774-9. doi: 10.1073/pnas.1504276112. Epub 2015 Aug 10. Proc Natl Acad Sci U S A. 2015. PMID: 26261340 Free PMC article.
Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer.
Marastoni S, Madariaga A, Pesic A, Nair SN, Li ZJ, Shalev Z, Ketela T, Colombo I, Mandilaras V, Cabanero M, Bruce JP, Li X, Garg S, Wang L, Chen EX, Gill S, Dhani NC, Zhang W, Pintilie M, Bowering V, Koritzinsky M, Rottapel R, Wouters BG, Oza AM, Joshua AM, Lheureux S. Marastoni S, et al. Among authors: koritzinsky m. Cancer Res Commun. 2022 May 4;2(5):293-306. doi: 10.1158/2767-9764.CRC-22-0037. eCollection 2022 May. Cancer Res Commun. 2022. PMID: 36875717 Free PMC article.
Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs.
Hunter FW, Young RJ, Shalev Z, Vellanki RN, Wang J, Gu Y, Joshi N, Sreebhavan S, Weinreb I, Goldstein DP, Moffat J, Ketela T, Brown KR, Koritzinsky M, Solomon B, Rischin D, Wilson WR, Wouters BG. Hunter FW, et al. Among authors: koritzinsky m. Cancer Res. 2015 Oct 1;75(19):4211-23. doi: 10.1158/0008-5472.CAN-15-1107. Epub 2015 Aug 21. Cancer Res. 2015. PMID: 26297733
Identifying the murine mammary cell target of metformin exposure.
Shehata M, Kim H, Vellanki R, Waterhouse PD, Mahendralingam M, Casey AE, Koritzinsky M, Khokha R. Shehata M, et al. Among authors: koritzinsky m. Commun Biol. 2019 May 20;2:192. doi: 10.1038/s42003-019-0439-x. eCollection 2019. Commun Biol. 2019. PMID: 31123716 Free PMC article.
Identification of acquired Notch3 dependency in metastatic Head and Neck Cancer.
Kondratyev M, Pesic A, Ketela T, Stickle N, Beswick C, Shalev Z, Marastoni S, Samadian S, Dvorkin-Gheva A, Sayad A, Bashkurov M, Boasquevisque P, Datti A, Pugh TJ, Virtanen C, Moffat J, Grénman RA, Koritzinsky M, Wouters BG. Kondratyev M, et al. Among authors: koritzinsky m. Commun Biol. 2023 May 18;6(1):538. doi: 10.1038/s42003-023-04828-9. Commun Biol. 2023. PMID: 37202533 Free PMC article.
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