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Structural mechanism of cGAS inhibition by the nucleosome.
Pathare GR, Decout A, Glück S, Cavadini S, Makasheva K, Hovius R, Kempf G, Weiss J, Kozicka Z, Guey B, Melenec P, Fierz B, Thomä NH, Ablasser A. Pathare GR, et al. Among authors: ablasser a. Nature. 2020 Nov;587(7835):668-672. doi: 10.1038/s41586-020-2750-6. Epub 2020 Sep 10. Nature. 2020. PMID: 32911482
Clathrin-associated AP-1 controls termination of STING signalling.
Liu Y, Xu P, Rivara S, Liu C, Ricci J, Ren X, Hurley JH, Ablasser A. Liu Y, et al. Among authors: ablasser a. Nature. 2022 Oct;610(7933):761-767. doi: 10.1038/s41586-022-05354-0. Epub 2022 Oct 19. Nature. 2022. PMID: 36261523 Free PMC article.
A carrier for cyclic dinucleotides.
Guey B, Ablasser A. Guey B, et al. Among authors: ablasser a. Nat Immunol. 2019 Nov;20(11):1418-1420. doi: 10.1038/s41590-019-0521-z. Nat Immunol. 2019. PMID: 31602042 No abstract available.
Emerging dimensions of cellular cGAS-STING signaling.
Guey B, Ablasser A. Guey B, et al. Among authors: ablasser a. Curr Opin Immunol. 2022 Feb;74:164-171. doi: 10.1016/j.coi.2022.01.004. Epub 2022 Feb 3. Curr Opin Immunol. 2022. PMID: 35124516 Review.
cGAS-STING drives ageing-related inflammation and neurodegeneration.
Gulen MF, Samson N, Keller A, Schwabenland M, Liu C, Glück S, Thacker VV, Favre L, Mangeat B, Kroese LJ, Krimpenfort P, Prinz M, Ablasser A. Gulen MF, et al. Among authors: ablasser a. Nature. 2023 Aug;620(7973):374-380. doi: 10.1038/s41586-023-06373-1. Epub 2023 Aug 2. Nature. 2023. PMID: 37532932 Free PMC article.
The cGAS-STING pathway and cancer.
Samson N, Ablasser A. Samson N, et al. Among authors: ablasser a. Nat Cancer. 2022 Dec;3(12):1452-1463. doi: 10.1038/s43018-022-00468-w. Epub 2022 Dec 12. Nat Cancer. 2022. PMID: 36510011 Review.
The cGAS-STING pathway drives type I IFN immunopathology in COVID-19.
Domizio JD, Gulen MF, Saidoune F, Thacker VV, Yatim A, Sharma K, Nass T, Guenova E, Schaller M, Conrad C, Goepfert C, de Leval L, Garnier CV, Berezowska S, Dubois A, Gilliet M, Ablasser A. Domizio JD, et al. Among authors: ablasser a. Nature. 2022 Mar;603(7899):145-151. doi: 10.1038/s41586-022-04421-w. Epub 2022 Jan 19. Nature. 2022. PMID: 35045565 Free PMC article.
60 results