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Bile Acid Metabolism Mediates Cholesterol Homeostasis and Promotes Tumorigenesis in Clear Cell Renal Cell Carcinoma.
Riscal R, Gardner SM, Coffey NJ, Carens M, Mesaros C, Xu JP, Xue Y, Davis L, Demczyszyn S, Vogt A, Olia A, Finan JM, Godfrey J, Schultz DC, Blair IA, Keith B, Marmorstein R, Skuli N, Simon MC. Riscal R, et al. Among authors: skuli n. Cancer Res. 2024 May 15;84(10):1570-1582. doi: 10.1158/0008-5472.CAN-23-0821. Cancer Res. 2024. PMID: 38417134
Cholesterol Auxotrophy as a Targetable Vulnerability in Clear Cell Renal Cell Carcinoma.
Riscal R, Bull CJ, Mesaros C, Finan JM, Carens M, Ho ES, Xu JP, Godfrey J, Brennan P, Johansson M, Purdue MP, Chanock SJ, Mariosa D, Timpson NJ, Vincent EE, Keith B, Blair IA, Skuli N, Simon MC. Riscal R, et al. Among authors: skuli n. Cancer Discov. 2021 Dec 1;11(12):3106-3125. doi: 10.1158/2159-8290.CD-21-0211. Cancer Discov. 2021. PMID: 34244212 Free PMC article.
Hypoxia-induced angiogenesis: good and evil.
Krock BL, Skuli N, Simon MC. Krock BL, et al. Among authors: skuli n. Genes Cancer. 2011 Dec;2(12):1117-33. doi: 10.1177/1947601911423654. Genes Cancer. 2011. PMID: 22866203 Free PMC article.
Metabolic Enzyme DLST Promotes Tumor Aggression and Reveals a Vulnerability to OXPHOS Inhibition in High-Risk Neuroblastoma.
Anderson NM, Qin X, Finan JM, Lam A, Athoe J, Missiaen R, Skuli N, Kennedy A, Saini AS, Tao T, Zhu S, Nissim I, Look AT, Qing G, Simon MC, Feng H. Anderson NM, et al. Among authors: skuli n. Cancer Res. 2021 Sep 1;81(17):4417-4430. doi: 10.1158/0008-5472.CAN-20-2153. Epub 2021 Jul 7. Cancer Res. 2021. PMID: 34233924 Free PMC article.
Even Cancer Cells Watch Their Cholesterol!
Riscal R, Skuli N, Simon MC. Riscal R, et al. Among authors: skuli n. Mol Cell. 2019 Oct 17;76(2):220-231. doi: 10.1016/j.molcel.2019.09.008. Epub 2019 Oct 2. Mol Cell. 2019. PMID: 31586545 Free PMC article. Review.
64 results