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Reframing sepsis immunobiology for translation: towards informative subtyping and targeted immunomodulatory therapies.
Shankar-Hari M, Calandra T, Soares MP, Bauer M, Wiersinga WJ, Prescott HC, Knight JC, Baillie KJ, Bos LDJ, Derde LPG, Finfer S, Hotchkiss RS, Marshall J, Openshaw PJM, Seymour CW, Venet F, Vincent JL, Le Tourneau C, Maitland-van der Zee AH, McInnes IB, van der Poll T. Shankar-Hari M, et al. Among authors: hotchkiss rs. Lancet Respir Med. 2024 Apr;12(4):323-336. doi: 10.1016/S2213-2600(23)00468-X. Epub 2024 Feb 23. Lancet Respir Med. 2024. PMID: 38408467 Free PMC article. Review.
Temporal Changes in Innate and Adaptive Immunity During Sepsis as Determined by ELISpot.
Unsinger J, Osborne D, Walton AH, Han E, Sheets L, Mazer MB, Remy KE, Griffith TS, Rao M, Badovinac VP, Brackenridge SC, Turnbull I, Efron PA, Moldawer LL, Caldwell CC, Hotchkiss RS. Unsinger J, et al. Among authors: hotchkiss rs. Shock. 2024 May 3. doi: 10.1097/SHK.0000000000002377. Online ahead of print. Shock. 2024. PMID: 38754032
Temporal Changes in Innate and Adaptive Immunity During Sepsis as Determined by ELISpot.
Unsinger J, Osborne D, Walton AH, Han E, Sheets L, Mazer MB, Remy KE, Griffith TS, Rao M, Badovinac VP, Brackenridge SC, Turnbull I, Efron PA, Moldawer LL, Caldwell CC, Hotchkiss RS. Unsinger J, et al. Among authors: hotchkiss rs. bioRxiv [Preprint]. 2023 Dec 14:2023.12.14.571668. doi: 10.1101/2023.12.14.571668. bioRxiv. 2023. PMID: 38168302 Free PMC article. Updated. Preprint.
Adverse outcomes and an immunosuppressed endotype in septic patients with reduced IFN-γ ELISpot.
Barrios EL, Mazer MB, McGonagill PW, Bergmann CB, Goodman MD, Gould RW, Rao M, Polcz VE, Davis RJ, Del Toro DE, Dirain ML, Dram A, Hale LO, Heidarian M, Kim CY, Kucaba TA, Lanz JP, McCray AE, Meszaros S, Miles S, Nelson CR, Rocha IL, Silva EE, Ungaro RF, Walton AH, Xu J, Zeumer-Spataro L, Drewry AM, Liang M, Bible LE, Loftus TJ, Turnbull IR, Efron PA, Remy KE, Brakenridge SC, Badovinac VP, Griffith TS, Moldawer LL, Hotchkiss RS, Caldwell CC. Barrios EL, et al. Among authors: hotchkiss rs. JCI Insight. 2024 Jan 23;9(2):e175785. doi: 10.1172/jci.insight.175785. JCI Insight. 2024. PMID: 38100268 Free PMC article.
Adverse Long-Term Outcomes and an Immune Suppressed Endotype in Sepsis Patients with Reduced Interferon-γELISpot: A Multicenter, Prospective Observational Study.
Barrios EA, Mazer MB, McGonagill P, Bergmann CB, Goodman MD, Gould R, Rao M, Polcz V, Davis R, Del Toro D, Dirain M, Dram A, Hale L, Heidarian M, Kucaba TA, Lanz JP, McCray A, Meszaros S, Miles S, Nelson C, Rocha I, Silva EE, Ungaro R, Walton A, Xu J, Zeumer-Spataro L, Drewry A, Liang M, Bible LE, Loftus T, Turnbull I, Efron PA, Remy KE, Brakenridge S, Badovinac VP, Griffith TS, Moldawer LL, Hotchkiss RS, Caldwell CC. Barrios EA, et al. Among authors: hotchkiss rs. medRxiv [Preprint]. 2023 Sep 24:2023.09.13.23295360. doi: 10.1101/2023.09.13.23295360. medRxiv. 2023. PMID: 37745385 Free PMC article. Updated. Preprint.
COVID-19 disease and immune dysregulation.
Davitt E, Davitt C, Mazer MB, Areti SS, Hotchkiss RS, Remy KE. Davitt E, et al. Among authors: hotchkiss rs. Best Pract Res Clin Haematol. 2022 Sep;35(3):101401. doi: 10.1016/j.beha.2022.101401. Epub 2022 Oct 15. Best Pract Res Clin Haematol. 2022. PMID: 36494149 Free PMC article. Review.
Lymphopenia in sepsis-an acquired immunodeficiency?
Finfer S, Venkatesh B, Hotchkiss RS, Sasson SC. Finfer S, et al. Among authors: hotchkiss rs. Immunol Cell Biol. 2023 Jul;101(6):535-544. doi: 10.1111/imcb.12611. Epub 2022 Dec 16. Immunol Cell Biol. 2023. PMID: 36468797 Review.
303 results