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RNA-Templated Peptide Bond Formation Promotes L-Homochirality.
Węgrzyn E, Mejdrová I, Müller FM, Nainytė M, Escobar L, Carell T. Węgrzyn E, et al. Among authors: carell t. Angew Chem Int Ed Engl. 2024 May 6;63(19):e202319235. doi: 10.1002/anie.202319235. Epub 2024 Apr 5. Angew Chem Int Ed Engl. 2024. PMID: 38407532
Lysosomal endonuclease RNase T2 and PLD exonucleases cooperatively generate RNA ligands for TLR7 activation.
Bérouti M, Lammens K, Heiss M, Hansbauer L, Bauernfried S, Stöckl J, Pinci F, Piseddu I, Greulich W, Wang M, Jung C, Fröhlich T, Carell T, Hopfner KP, Hornung V. Bérouti M, et al. Among authors: carell t. Immunity. 2024 Apr 26:S1074-7613(24)00215-2. doi: 10.1016/j.immuni.2024.04.010. Online ahead of print. Immunity. 2024. PMID: 38697119 Free article.
Depletion of pyruvate kinase (PK) activity causes glycolytic intermediate imbalances and reveals a PK-TXNIP regulatory axis.
Nieborak A, Lukauskas S, Capellades J, Heyn P, Santos GS, Motzler K, Zeigerer A, Bester R, Protzer U, Schelter F, Wagner M, Carell T, Hruscha A, Schmid B, Yanes O, Schneider R. Nieborak A, et al. Among authors: carell t. Mol Metab. 2023 Aug;74:101748. doi: 10.1016/j.molmet.2023.101748. Epub 2023 Jun 7. Mol Metab. 2023. PMID: 37290673 Free PMC article.
Synthesis and Structure Elucidation of Glutamyl-Queuosine.
Pichler A, Hillmeier M, Heiss M, Peev E, Xefteris S, Steigenberger B, Thoma I, Müller M, Borsò M, Imhof A, Carell T. Pichler A, et al. Among authors: carell t. J Am Chem Soc. 2023 Nov 29;145(47):25528-25532. doi: 10.1021/jacs.3c10075. Epub 2023 Nov 15. J Am Chem Soc. 2023. PMID: 37967838 Free PMC article.
Experience with German Research Consortia in the Field of Chemical Biology of Native Nucleic Acid Modifications.
Helm M, Bohnsack MT, Carell T, Dalpke A, Entian KD, Ehrenhofer-Murray A, Ficner R, Hammann C, Höbartner C, Jäschke A, Jeltsch A, Kaiser S, Klassen R, Leidel SA, Marx A, Mörl M, Meier JC, Meister G, Rentmeister A, Rodnina M, Roignant JY, Schaffrath R, Stadler P, Stafforst T. Helm M, et al. Among authors: carell t. ACS Chem Biol. 2023 Dec 15;18(12):2441-2449. doi: 10.1021/acschembio.3c00586. Epub 2023 Nov 14. ACS Chem Biol. 2023. PMID: 37962075 Review.
Human TRMT2A methylates tRNA and contributes to translation fidelity.
Witzenberger M, Burczyk S, Settele D, Mayer W, Welp LM, Heiss M, Wagner M, Monecke T, Janowski R, Carell T, Urlaub H, Hauck SM, Voigt A, Niessing D. Witzenberger M, et al. Among authors: carell t. Nucleic Acids Res. 2023 Sep 8;51(16):8691-8710. doi: 10.1093/nar/gkad565. Nucleic Acids Res. 2023. PMID: 37395448 Free PMC article.
Loading of Amino Acids onto RNA in a Putative RNA-Peptide World.
Singer JN, Müller FM, Węgrzyn E, Hölzl C, Hurmiz H, Liu C, Escobar L, Carell T. Singer JN, et al. Among authors: carell t. Angew Chem Int Ed Engl. 2023 May 15;62(21):e202302360. doi: 10.1002/anie.202302360. Epub 2023 Apr 17. Angew Chem Int Ed Engl. 2023. PMID: 36881520
300 results