Ott I - Search Results

1

Paraptotic Cell Death as an Unprecedented Mode of Action Observed for New Bipyridine-Silver(I) Compounds Bearing Phosphane Coligands.

Teixeira RG, Stefanelli A, Pilon A, Warmers R, Fontrodona X, Romero I, Costa PJ, Villa de Brito MJ, Hudec X, Pirker C, Türck S, Antunes AMM, Kowol CR, Ott I, Brozovic A, Sombke A, Eckhard M, Tomaz AI, Heffeter P, Valente A. Teixeira RG, et al. Among authors: ott i. J Med Chem. 2024 Apr 25;67(8):6081-6098. doi: 10.1021/acs.jmedchem.3c01036. Epub 2024 Feb 24. J Med Chem. 2024. PMID: 38401050 Free PMC article.

2

Benzimidazol-2-ylidene gold(I) complexes are thioredoxin reductase inhibitors with multiple antitumor properties.

Rubbiani R, Kitanovic I, Alborzinia H, Can S, Kitanovic A, Onambele LA, Stefanopoulou M, Geldmacher Y, Sheldrick WS, Wolber G, Prokop A, Wölfl S, Ott I. Rubbiani R, et al. Among authors: ott i. J Med Chem. 2010 Dec 23;53(24):8608-18. doi: 10.1021/jm100801e. Epub 2010 Nov 17. J Med Chem. 2010. PMID: 21082862

3

Comparative in vitro evaluation of N-heterocyclic carbene gold(I) complexes of the benzimidazolylidene type.

Rubbiani R, Can S, Kitanovic I, Alborzinia H, Stefanopoulou M, Kokoschka M, Mönchgesang S, Sheldrick WS, Wölfl S, Ott I. Rubbiani R, et al. Among authors: ott i. J Med Chem. 2011 Dec 22;54(24):8646-57. doi: 10.1021/jm201220n. Epub 2011 Nov 17. J Med Chem. 2011. PMID: 22039997

4

Gold Metallodrugs to Target Coronavirus Proteins: Inhibitory Effects on the Spike-ACE2 Interaction and on PLpro Protease Activity by Auranofin and Gold Organometallics*.

Gil-Moles M, Basu U, Büssing R, Hoffmeister H, Türck S, Varchmin A, Ott I. Gil-Moles M, et al. Among authors: ott i. Chemistry. 2020 Nov 26;26(66):15140-15144. doi: 10.1002/chem.202004112. Epub 2020 Oct 19. Chemistry. 2020. PMID: 32915473 Free PMC article.

5

Taming the Biological Activity of Pd(II) and Pt(II) Complexes with Triazolato "Protective" Groups: ¹H, ⁷⁷Se Nuclear Magnetic Resonance and X-ray Crystallographic Model Studies with Selenocysteine to Elucidate Differential Thioredoxin Reductase Inhibition.

Müller VVL, Simpson PV, Peng K, Basu U, Moreth D, Nagel C, Türck S, Oehninger L, Ott I, Schatzschneider U. Müller VVL, et al. Among authors: ott i. Inorg Chem. 2023 Oct 2;62(39):16203-16214. doi: 10.1021/acs.inorgchem.3c02701. Epub 2023 Sep 15. Inorg Chem. 2023. PMID: 37713601

6

Substituted pyridazino[3,4-b][1,5]benzoxazepin-5(6H)ones as multidrug-resistance modulating agents.

Ott I, Kircher B, Heinisch G, Matuszczak B. Ott I, et al. J Med Chem. 2004 Aug 26;47(18):4627-30. doi: 10.1021/jm040803n. J Med Chem. 2004. PMID: 15317472

7

Comparative biological evaluation of two ethylene linked mixed binuclear ferrocene/ruthenium organometallic species.

Ott I, Kowalski K, Gust R, Maurer J, Mücke P, Winter RF. Ott I, et al. Bioorg Med Chem Lett. 2010 Feb 1;20(3):866-9. doi: 10.1016/j.bmcl.2009.12.080. Epub 2009 Dec 28. Bioorg Med Chem Lett. 2010. PMID: 20074947

8

Ferrocenyl bioconjugates of ampicillin and 6-aminopenicillinic acid--synthesis, electrochemistry and biological activity.

Skiba J, Rajnisz A, de Oliveira KN, Ott I, Solecka J, Kowalski K. Skiba J, et al. Among authors: ott i. Eur J Med Chem. 2012 Nov;57:234-9. doi: 10.1016/j.ejmech.2012.09.023. Epub 2012 Sep 23. Eur J Med Chem. 2012. PMID: 23072737

9

Metal complexes with 2-acetylpyridine-N(4)-orthochlorophenylthiosemicarbazone: cytotoxicity and effect on the enzymatic activity of thioredoxin reductase and glutathione reductase.

Parrilha GL, Ferraz KS, Lessa JA, de Oliveira KN, Rodrigues BL, Ramos JP, Souza-Fagundes EM, Ott I, Beraldo H. Parrilha GL, et al. Among authors: ott i. Eur J Med Chem. 2014 Sep 12;84:537-44. doi: 10.1016/j.ejmech.2014.07.055. Epub 2014 Jul 17. Eur J Med Chem. 2014. PMID: 25058344

10

Organotin complexes containing carboxylate ligands with maleimide and naphthalimide derived partial structures: TrxR inhibition, cytotoxicity and activity in resistant cancer cells.

Navakoski de Oliveira K, Andermark V, Onambele LA, Dahl G, Prokop A, Ott I. Navakoski de Oliveira K, et al. Among authors: ott i. Eur J Med Chem. 2014 Nov 24;87:794-800. doi: 10.1016/j.ejmech.2014.09.075. Epub 2014 Sep 28. Eur J Med Chem. 2014. PMID: 25440880

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