Kowol CR - Search Results

1

Paraptotic Cell Death as an Unprecedented Mode of Action Observed for New Bipyridine-Silver(I) Compounds Bearing Phosphane Coligands.

Teixeira RG, Stefanelli A, Pilon A, Warmers R, Fontrodona X, Romero I, Costa PJ, Villa de Brito MJ, Hudec X, Pirker C, Türck S, Antunes AMM, Kowol CR, Ott I, Brozovic A, Sombke A, Eckhard M, Tomaz AI, Heffeter P, Valente A. Teixeira RG, et al. Among authors: kowol cr. J Med Chem. 2024 Apr 25;67(8):6081-6098. doi: 10.1021/acs.jmedchem.3c01036. Epub 2024 Feb 24. J Med Chem. 2024. PMID: 38401050 Free PMC article.

2

Comparative studies on the human serum albumin binding of the clinically approved EGFR inhibitors gefitinib, erlotinib, afatinib, osimertinib and the investigational inhibitor KP2187.

Dömötör O, Pelivan K, Borics A, Keppler BK, Kowol CR, Enyedy ÉA. Dömötör O, et al. Among authors: kowol cr. J Pharm Biomed Anal. 2018 May 30;154:321-331. doi: 10.1016/j.jpba.2018.03.011. Epub 2018 Mar 11. J Pharm Biomed Anal. 2018. PMID: 29567575 Free article.

3

Preclinical characterization of anticancer gallium(III) complexes: solubility, stability, lipophilicity and binding to serum proteins.

Rudnev AV, Foteeva LS, Kowol C, Berger R, Jakupec MA, Arion VB, Timerbaev AR, Keppler BK. Rudnev AV, et al. J Inorg Biochem. 2006 Nov;100(11):1819-26. doi: 10.1016/j.jinorgbio.2006.07.003. Epub 2006 Jul 25. J Inorg Biochem. 2006. PMID: 16938349

4

A quantitative structure-activity approach for lipophilicity estimation of antitumor complexes of different metals using microemulsion electrokinetic chromatography.

Foteeva LS, Trofimov DA, Kuznetsova OV, Kowol CR, Arion VB, Keppler BK, Timerbaev AR. Foteeva LS, et al. Among authors: kowol cr. J Pharm Biomed Anal. 2011 Jun 1;55(3):409-13. doi: 10.1016/j.jpba.2011.02.011. Epub 2011 Feb 17. J Pharm Biomed Anal. 2011. PMID: 21382684

5

Ribonucleotide reductase inhibition by metal complexes of Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone): a combined experimental and theoretical study.

Popović-Bijelić A, Kowol CR, Lind ME, Luo J, Himo F, Enyedy EA, Arion VB, Gräslund A. Popović-Bijelić A, et al. Among authors: kowol cr. J Inorg Biochem. 2011 Nov;105(11):1422-31. doi: 10.1016/j.jinorgbio.2011.07.003. Epub 2011 Jul 31. J Inorg Biochem. 2011. PMID: 21955844 Free PMC article.

6

Interaction of Triapine and related thiosemicarbazones with iron(III)/(II) and gallium(III): a comparative solution equilibrium study.

Enyedy ÉA, Primik MF, Kowol CR, Arion VB, Kiss T, Keppler BK. Enyedy ÉA, et al. Among authors: kowol cr. Dalton Trans. 2011 Jun 14;40(22):5895-905. doi: 10.1039/c0dt01835j. Epub 2011 Apr 27. Dalton Trans. 2011. PMID: 21523301 Free PMC article.

7

Gallium(III) and iron(III) complexes of alpha-N-heterocyclic thiosemicarbazones: synthesis, characterization, cytotoxicity, and interaction with ribonucleotide reductase.

Kowol CR, Berger R, Eichinger R, Roller A, Jakupec MA, Schmidt PP, Arion VB, Keppler BK. Kowol CR, et al. J Med Chem. 2007 Mar 22;50(6):1254-65. doi: 10.1021/jm0612618. Epub 2007 Feb 22. J Med Chem. 2007. PMID: 17315858

8

Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation.

Kowol CR, Trondl R, Heffeter P, Arion VB, Jakupec MA, Roller A, Galanski MS, Berger W, Keppler BK. Kowol CR, et al. J Med Chem. 2009 Aug 27;52(16):5032-43. doi: 10.1021/jm900528d. J Med Chem. 2009. PMID: 19637923

9

Anticancer activity of metal complexes: involvement of redox processes.

Jungwirth U, Kowol CR, Keppler BK, Hartinger CG, Berger W, Heffeter P. Jungwirth U, et al. Among authors: kowol cr. Antioxid Redox Signal. 2011 Aug 15;15(4):1085-127. doi: 10.1089/ars.2010.3663. Epub 2011 May 11. Antioxid Redox Signal. 2011. PMID: 21275772 Free PMC article. Review.

10

Mechanisms underlying reductant-induced reactive oxygen species formation by anticancer copper(II) compounds.

Kowol CR, Heffeter P, Miklos W, Gille L, Trondl R, Cappellacci L, Berger W, Keppler BK. Kowol CR, et al. J Biol Inorg Chem. 2012 Mar;17(3):409-23. doi: 10.1007/s00775-011-0864-x. Epub 2011 Dec 22. J Biol Inorg Chem. 2012. PMID: 22189939 Free PMC article.

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