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Incremental value of serum neurofilament light chain and glial fibrillary acidic protein as blood-based biomarkers for predicting functional outcome in severe acute ischemic stroke.
Vollmuth C, Fiessler C, Montellano FA, Kollikowski AM, Essig F, Oeckl P, Barba L, Steinacker P, Schulz C, Ungethüm K, Wolf J, Pham M, Schuhmann MK, Heuschmann PU, Haeusler KG, Stoll G, Otto M, Neugebauer H. Vollmuth C, et al. Among authors: schuhmann mk. Eur Stroke J. 2024 Feb 24:23969873241234436. doi: 10.1177/23969873241234436. Online ahead of print. Eur Stroke J. 2024. PMID: 38400734 Free article.
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature.
Kleinschnitz C, Kraft P, Dreykluft A, Hagedorn I, Göbel K, Schuhmann MK, Langhauser F, Helluy X, Schwarz T, Bittner S, Mayer CT, Brede M, Varallyay C, Pham M, Bendszus M, Jakob P, Magnus T, Meuth SG, Iwakura Y, Zernecke A, Sparwasser T, Nieswandt B, Stoll G, Wiendl H. Kleinschnitz C, et al. Among authors: schuhmann mk. Blood. 2013 Jan 24;121(4):679-91. doi: 10.1182/blood-2012-04-426734. Epub 2012 Nov 15. Blood. 2013. PMID: 23160472 Free PMC article.
Blocking of α4 integrin does not protect from acute ischemic stroke in mice.
Langhauser F, Kraft P, Göb E, Leinweber J, Schuhmann MK, Lorenz K, Gelderblom M, Bittner S, Meuth SG, Wiendl H, Magnus T, Kleinschnitz C. Langhauser F, et al. Among authors: schuhmann mk. Stroke. 2014 Jun;45(6):1799-806. doi: 10.1161/STROKEAHA.114.005000. Epub 2014 Apr 17. Stroke. 2014. PMID: 24743435
CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke.
Schuhmann MK, Kraft P, Stoll G, Lorenz K, Meuth SG, Wiendl H, Nieswandt B, Sparwasser T, Beyersdorf N, Kerkau T, Kleinschnitz C. Schuhmann MK, et al. J Cereb Blood Flow Metab. 2015 Jan;35(1):6-10. doi: 10.1038/jcbfm.2014.175. Epub 2014 Oct 15. J Cereb Blood Flow Metab. 2015. PMID: 25315859 Free PMC article.
Blocking of plasma kallikrein ameliorates stroke by reducing thromboinflammation.
Göb E, Reymann S, Langhauser F, Schuhmann MK, Kraft P, Thielmann I, Göbel K, Brede M, Homola G, Solymosi L, Stoll G, Geis C, Meuth SG, Nieswandt B, Kleinschnitz C. Göb E, et al. Among authors: schuhmann mk. Ann Neurol. 2015 May;77(5):784-803. doi: 10.1002/ana.24380. Epub 2015 Mar 13. Ann Neurol. 2015. PMID: 25628066
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