Wagner S - Search Results

1

An Antiherpesviral Host-Directed Strategy Based on CDK7 Covalently Binding Drugs: Target-Selective, Picomolar-Dose, Cross-Virus Reactivity.

Yu D, Wagner S, Schütz M, Jeon Y, Seo M, Kim J, Brückner N, Kicuntod J, Tillmanns J, Wangen C, Hahn F, Kaufer BB, Neipel F, Eickhoff J, Klebl B, Nam K, Marschall M. Yu D, et al. Among authors: wagner s. Pharmaceutics. 2024 Jan 23;16(2):158. doi: 10.3390/pharmaceutics16020158. Pharmaceutics. 2024. PMID: 38399219 Free PMC article.

2

Combined Treatment with Host-Directed and Anticytomegaloviral Kinase Inhibitors: Mechanisms, Synergisms and Drug Resistance Barriers.

Wild M, Karner D, Eickhoff J, Wagner S, Kicuntod J, Chang W, Barry P, Jonjić S, Lenac Roviš T, Marschall M. Wild M, et al. Among authors: wagner s. Pharmaceutics. 2023 Nov 27;15(12):2680. doi: 10.3390/pharmaceutics15122680. Pharmaceutics. 2023. PMID: 38140021 Free PMC article.

3

Combinatorial Drug Treatments Reveal Promising Anticytomegaloviral Profiles for Clinically Relevant Pharmaceutical Kinase Inhibitors (PKIs).

Wild M, Kicuntod J, Seyler L, Wangen C, Bertzbach LD, Conradie AM, Kaufer BB, Wagner S, Michel D, Eickhoff J, Tsogoeva SB, Bäuerle T, Hahn F, Marschall M. Wild M, et al. Among authors: wagner s. Int J Mol Sci. 2021 Jan 8;22(2):575. doi: 10.3390/ijms22020575. Int J Mol Sci. 2021. PMID: 33430060 Free PMC article.

4

Cyclin-Dependent Kinases (CDKs) and the Human Cytomegalovirus-Encoded CDK Ortholog pUL97 Represent Highly Attractive Targets for Synergistic Drug Combinations.

Wild M, Hahn F, Brückner N, Schütz M, Wangen C, Wagner S, Sommerer M, Strobl S, Marschall M. Wild M, et al. Among authors: wagner s. Int J Mol Sci. 2022 Feb 24;23(5):2493. doi: 10.3390/ijms23052493. Int J Mol Sci. 2022. PMID: 35269635 Free PMC article.

5

Assessment of Covalently Binding Warhead Compounds in the Validation of the Cytomegalovirus Nuclear Egress Complex as an Antiviral Target.

Tillmanns J, Häge S, Borst EM, Wardin J, Eickhoff J, Klebl B, Wagner S, Wangen C, Hahn F, Socher E, Marschall M. Tillmanns J, et al. Among authors: wagner s. Cells. 2023 Apr 14;12(8):1162. doi: 10.3390/cells12081162. Cells. 2023. PMID: 37190072 Free PMC article.

6

A novel CDK7 inhibitor of the Pyrazolotriazine class exerts broad-spectrum antiviral activity at nanomolar concentrations.

Hutterer C, Eickhoff J, Milbradt J, Korn K, Zeitträger I, Bahsi H, Wagner S, Zischinsky G, Wolf A, Degenhart C, Unger A, Baumann M, Klebl B, Marschall M. Hutterer C, et al. Among authors: wagner s. Antimicrob Agents Chemother. 2015 Apr;59(4):2062-71. doi: 10.1128/AAC.04534-14. Epub 2015 Jan 26. Antimicrob Agents Chemother. 2015. PMID: 25624324 Free PMC article.

7

'Shared-Hook' and 'Changed-Hook' Binding Activities of Herpesviral Core Nuclear Egress Complexes Identified by Random Mutagenesis.

Lösing J, Häge S, Schütz M, Wagner S, Wardin J, Sticht H, Marschall M. Lösing J, et al. Among authors: wagner s. Cells. 2022 Dec 13;11(24):4030. doi: 10.3390/cells11244030. Cells. 2022. PMID: 36552794 Free PMC article.

8

The peptidyl-prolyl cis/trans isomerase Pin1 interacts with three early regulatory proteins of human cytomegalovirus.

Schütz M, Thomas M, Wangen C, Wagner S, Rauschert L, Errerd T, Kießling M, Sticht H, Milbradt J, Marschall M. Schütz M, et al. Among authors: wagner s. Virus Res. 2020 Aug;285:198023. doi: 10.1016/j.virusres.2020.198023. Epub 2020 May 16. Virus Res. 2020. PMID: 32428517

9

Functional Relevance of the Interaction between Human Cyclins and the Cytomegalovirus-Encoded CDK-Like Protein Kinase pUL97.

Schütz M, Steingruber M, Socher E, Müller R, Wagner S, Kögel M, Sticht H, Marschall M. Schütz M, et al. Among authors: wagner s. Viruses. 2021 Jun 27;13(7):1248. doi: 10.3390/v13071248. Viruses. 2021. PMID: 34198986 Free PMC article.

10

The Prolyl Isomerase Pin1 Promotes the Herpesvirus-Induced Phosphorylation-Dependent Disassembly of the Nuclear Lamina Required for Nucleocytoplasmic Egress.

Milbradt J, Hutterer C, Bahsi H, Wagner S, Sonntag E, Horn AH, Kaufer BB, Mori Y, Sticht H, Fossen T, Marschall M. Milbradt J, et al. Among authors: wagner s. PLoS Pathog. 2016 Aug 24;12(8):e1005825. doi: 10.1371/journal.ppat.1005825. eCollection 2016 Aug. PLoS Pathog. 2016. PMID: 27556400 Free PMC article.

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