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A CD38-directed, single-chain T-cell engager targets leukemia stem cells through IFN-γ-induced CD38 expression.
Murtadha M, Park M, Zhu Y, Caserta E, Napolitano O, Tandoh T, Moloudizargari M, Pozhitkov A, Singer M, Dona AA, Vahed H, Gonzalez A, Ly K, Ouyang C, Sanchez JF, Nigam L, Duplan A, Chowdhury A, Ghoda L, Li L, Zhang B, Krishnan A, Marcucci G, Williams JC, Pichiorri F. Murtadha M, et al. Among authors: pozhitkov a. Blood. 2024 Apr 18;143(16):1599-1615. doi: 10.1182/blood.2023021570. Blood. 2024. PMID: 38394668
Leflunomide regulates c-Myc expression in myeloma cells through PIM targeting.
Buettner R, Morales C, Caserta E, Troadec E, Gunes EG, Viola D, Khalife J, Li H, Keats JJ, Christofferson A, Wu X, Synold TW, Palmer J, Sanchez JF, Pozhitkov A, Vaidehi N, Marcucci G, Krishnan A, Rosenzweig MA, Pichiorri F, Rosen ST. Buettner R, et al. Among authors: pozhitkov a. Blood Adv. 2019 Apr 9;3(7):1027-1032. doi: 10.1182/bloodadvances.2018027227. Blood Adv. 2019. PMID: 30940637 Free PMC article.
MiR-16 regulates crosstalk in NF-κB tolerogenic inflammatory signaling between myeloma cells and bone marrow macrophages.
Khalife J, Ghose J, Martella M, Viola D, Rocci A, Troadec E, Terrazas C, Satoskar AR, Gunes EG, Dona A, Sanchez JF, Bergsagel PL, Chesi M, Pozhitkov A, Rosen S, Marcucci G, Keats JJ, Hofmeister CC, Krishnan A, Caserta E, Pichiorri F. Khalife J, et al. Among authors: pozhitkov a. JCI Insight. 2019 Nov 1;4(21):e129348. doi: 10.1172/jci.insight.129348. JCI Insight. 2019. PMID: 31593552 Free PMC article.
Association between Clonal Hematopoiesis and Late Nonrelapse Mortality after Autologous Hematopoietic Cell Transplantation.
Slavin TP, Teh JB, Weitzel JN, Peng K, Wong FL, Qin H, Wang J, Wu X, Mei M, Pillai R, Wang Y, Tsang KK, Pozhitkov A, Krishnan A, Forman SJ, Armenian SH. Slavin TP, et al. Among authors: pozhitkov a. Biol Blood Marrow Transplant. 2019 Dec;25(12):2517-2521. doi: 10.1016/j.bbmt.2019.08.013. Epub 2019 Aug 22. Biol Blood Marrow Transplant. 2019. PMID: 31445185 Free PMC article.
Essential role of the histone lysine demethylase KDM4A in the biology of malignant pleural mesothelioma (MPM).
Lapidot M, Case AE, Weisberg EL, Meng C, Walker SR, Garg S, Ni W, Podar K, Hung YP, Carrasco RD, Knott A, Gokhale PC, Sharma S, Pozhitkov A, Kulkarni P, Frank DA, Salgia R, Griffin JD, Saladi SV, Bueno R, Sattler M. Lapidot M, et al. Among authors: pozhitkov a. Br J Cancer. 2021 Aug;125(4):582-592. doi: 10.1038/s41416-021-01441-7. Epub 2021 Jun 4. Br J Cancer. 2021. PMID: 34088988 Free PMC article.
Effects of selected deubiquitinating enzyme inhibitors on the proliferation and motility of lung cancer and mesothelioma cell lines.
Mirzapoiazova T, Pozhitkov A, Nam A, Mambetsariev I, Nelson MS, Tan YC, Zhang K, Raz D, Singhal S, Nasser MW, Kulkarni P, Batra SK, Sattler M, Salgia R. Mirzapoiazova T, et al. Among authors: pozhitkov a. Int J Oncol. 2020 Jul;57(1):80-86. doi: 10.3892/ijo.2020.5034. Epub 2020 Apr 1. Int J Oncol. 2020. PMID: 32236606 Free PMC article.
A Non-genetic Mechanism Involving the Integrin β4/Paxillin Axis Contributes to Chemoresistance in Lung Cancer.
Mohanty A, Nam A, Pozhitkov A, Yang L, Srivastava S, Nathan A, Wu X, Mambetsariev I, Nelson M, Subbalakshmi AR, Guo L, Nasser MW, Batra SK, Orban J, Jolly MK, Massarelli E, Kulkarni P, Salgia R. Mohanty A, et al. Among authors: pozhitkov a. iScience. 2020 Aug 22;23(9):101496. doi: 10.1016/j.isci.2020.101496. eCollection 2020 Sep 25. iScience. 2020. PMID: 32947124 Free PMC article.
Inhibiting crosstalk between MET signaling and mitochondrial dynamics and morphology: a novel therapeutic approach for lung cancer and mesothelioma.
Wang J, Mirzapoiazova T, Carol Tan YH, Pang KM, Pozhitkov A, Wang Y, Wang Y, Mambetsariev B, Wang E, Nasser MW, Batra SK, Raz D, Reckamp K, Kulkarni P, Zheng Y, Salgia R. Wang J, et al. Among authors: pozhitkov a. Cancer Biol Ther. 2018;19(11):1023-1032. doi: 10.1080/15384047.2018.1472193. Epub 2018 Oct 12. Cancer Biol Ther. 2018. PMID: 30311833 Free PMC article.
55 results