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Multi-target rational design and synthesis of novel diphenyl-tethered pyrazolopyrimidines targeting EGFR and topoisomerase II with potential DNA intercalation and apoptosis induction.
Gaber AA, Abo Elmaaty A, Sharaky M, Mosa AA, Yahya Abdullah Alzahrani A, Shaaban S, Eldehna WM, Al-Karmalawy AA. Gaber AA, et al. Among authors: yahya abdullah alzahrani a. Bioorg Chem. 2024 Apr;145:107223. doi: 10.1016/j.bioorg.2024.107223. Epub 2024 Feb 17. Bioorg Chem. 2024. PMID: 38387399
Synthesis, crystal structure and Hirshfeld surface analysis of 2-phenyl-3-(prop-2-yn-1-yl-oxy)quin-oxaline.
Abad N, Mague JT, Alsubari A, Essassi EM, Pourayoubi M, Yahya Abdullah Alzahrani A, Ramli Y. Abad N, et al. Among authors: yahya abdullah alzahrani a. Acta Crystallogr E Crystallogr Commun. 2024 Mar 21;80(Pt 4):383-387. doi: 10.1107/S2056989024002585. eCollection 2024 Mar 1. Acta Crystallogr E Crystallogr Commun. 2024. PMID: 38584742 Free PMC article.