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Targeting PI3K/Akt/mTOR signaling in rodent models of PMP22 gene-dosage diseases.
Krauter D, Stausberg D, Hartmann TJ, Volkmann S, Kungl T, Rasche DA, Saher G, Fledrich R, Stassart RM, Nave KA, Goebbels S, Ewers D, Sereda MW. Krauter D, et al. Among authors: kungl t. EMBO Mol Med. 2024 Mar;16(3):616-640. doi: 10.1038/s44321-023-00019-5. Epub 2024 Feb 21. EMBO Mol Med. 2024. PMID: 38383802 Free PMC article.
Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration.
Sundaram VK, Schütza V, Schröter NH, Backhaus A, Bilsing A, Joneck L, Seelbach A, Mutschler C, Gomez-Sanchez JA, Schäffner E, Sánchez EE, Akkermann D, Paul C, Schwagarus N, Müller S, Odle A, Childs G, Ewers D, Kungl T, Sitte M, Salinas G, Sereda MW, Nave KA, Schwab MH, Ost M, Arthur-Farraj P, Stassart RM, Fledrich R. Sundaram VK, et al. Among authors: kungl t. Cell Metab. 2023 Dec 5;35(12):2136-2152.e9. doi: 10.1016/j.cmet.2023.10.017. Epub 2023 Nov 20. Cell Metab. 2023. PMID: 37989315 Free PMC article.
Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease.
Schäffner E, Bosch-Queralt M, Edgar JM, Lehning M, Strauß J, Fleischer N, Kungl T, Wieghofer P, Berghoff SA, Reinert T, Krueger M, Morawski M, Möbius W, Barrantes-Freer A, Stieler J, Sun T, Saher G, Schwab MH, Wrede C, Frosch M, Prinz M, Reich DS, Flügel A, Stadelmann C, Fledrich R, Nave KA, Stassart RM. Schäffner E, et al. Among authors: kungl t. Nat Neurosci. 2023 Jul;26(7):1218-1228. doi: 10.1038/s41593-023-01366-9. Epub 2023 Jun 29. Nat Neurosci. 2023. PMID: 37386131 Free PMC article.
Publisher Correction: NRG1 type I dependent autoparacrine stimulation of Schwann cells in onion bulbs of peripheral neuropathies.
Fledrich R, Akkermann D, Schütza V, Abdelaal TA, Hermes D, Schäffner E, Soto-Bernardini MC, Götze T, Klink A, Kusch K, Krueger M, Kungl T, Frydrychowicz C, Möbius W, Brück W, Mueller WC, Bechmann I, Sereda MW, Schwab MH, Nave KA, Stassart RM. Fledrich R, et al. Among authors: kungl t. Nat Commun. 2019 Apr 16;10(1):1840. doi: 10.1038/s41467-019-09886-4. Nat Commun. 2019. PMID: 30992451 Free PMC article.
NRG1 type I dependent autoparacrine stimulation of Schwann cells in onion bulbs of peripheral neuropathies.
Fledrich R, Akkermann D, Schütza V, Abdelaal TA, Hermes D, Schäffner E, Soto-Bernardini MC, Götze T, Klink A, Kusch K, Krueger M, Kungl T, Frydrychowicz C, Möbius W, Brück W, Mueller WC, Bechmann I, Sereda MW, Schwab MH, Nave KA, Stassart RM. Fledrich R, et al. Among authors: kungl t. Nat Commun. 2019 Apr 1;10(1):1467. doi: 10.1038/s41467-019-09385-6. Nat Commun. 2019. PMID: 30931926 Free PMC article.
Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy.
Kleinecke S, Richert S, de Hoz L, Brügger B, Kungl T, Asadollahi E, Quintes S, Blanz J, McGonigal R, Naseri K, Sereda MW, Sachsenheimer T, Lüchtenborg C, Möbius W, Willison H, Baes M, Nave KA, Kassmann CM. Kleinecke S, et al. Among authors: kungl t. Elife. 2017 May 4;6:e23332. doi: 10.7554/eLife.23332. Elife. 2017. PMID: 28470148 Free PMC article.
Zeb2 is essential for Schwann cell differentiation, myelination and nerve repair.
Quintes S, Brinkmann BG, Ebert M, Fröb F, Kungl T, Arlt FA, Tarabykin V, Huylebroeck D, Meijer D, Suter U, Wegner M, Sereda MW, Nave KA. Quintes S, et al. Among authors: kungl t. Nat Neurosci. 2016 Aug;19(8):1050-1059. doi: 10.1038/nn.4321. Epub 2016 Jun 13. Nat Neurosci. 2016. PMID: 27294512 Free PMC article.
12 results