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Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies.
Nat Commun. 2024 Feb 21;15(1):1583. doi: 10.1038/s41467-024-45854-3.
Nat Commun. 2024.
PMID: 38383515
Free PMC article.
Designer Small-Molecule Control System Based on Minocycline-Induced Disruption of Protein-Protein Interaction.
Jha R, Kinna A, Hotblack A, Bughda R, Bulek A, Gannon I, Ilca T, Allen C, Lamb K, Dolor A, Scott I, Parekh F, Sillibourne J, Cordoba S, Onuoha S, Thomas S, Ferrari M, Pule M.
Jha R, et al. Among authors: bughda r.
ACS Chem Biol. 2024 Feb 16;19(2):308-324. doi: 10.1021/acschembio.3c00521. Epub 2024 Jan 20.
ACS Chem Biol. 2024.
PMID: 38243811
Free PMC article.
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Optimised Method for the Production and Titration of Lentiviral Vectors Pseudotyped with the SARS-CoV-2 Spike.
Mekkaoui L, Bentley EM, Ferrari M, Lamb K, Ward K, Karattil R, Akbar Z, Bughda R, Sillibourne J, Onuoha S, Mattiuzzo G, Takeuchi Y, Pule M.
Mekkaoui L, et al. Among authors: bughda r.
Bio Protoc. 2021 Aug 20;11(16):e4194. doi: 10.21769/BioProtoc.4194. eCollection 2021 Aug 20.
Bio Protoc. 2021.
PMID: 34541054
Free PMC article.
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Fibroblast Activation Protein (FAP)-Targeted CAR-T Cells: Launching an Attack on Tumor Stroma.
Bughda R, Dimou P, D'Souza RR, Klampatsa A.
Bughda R, et al.
Immunotargets Ther. 2021 Aug 5;10:313-323. doi: 10.2147/ITT.S291767. eCollection 2021.
Immunotargets Ther. 2021.
PMID: 34386436
Free PMC article.
Review.
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Characterization of a Novel ACE2-Based Therapeutic with Enhanced Rather than Reduced Activity against SARS-CoV-2 Variants.
Ferrari M, Mekkaoui L, Ilca FT, Akbar Z, Bughda R, Lamb K, Ward K, Parekh F, Karattil R, Allen C, Wu P, Baldan V, Mattiuzzo G, Bentley EM, Takeuchi Y, Sillibourne J, Datta P, Kinna A, Pule M, Onuoha SC.
Ferrari M, et al. Among authors: bughda r.
J Virol. 2021 Sep 9;95(19):e0068521. doi: 10.1128/JVI.00685-21. Epub 2021 Sep 9.
J Virol. 2021.
PMID: 34287040
Free PMC article.
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Combining phage display with SMRTbell next-generation sequencing for the rapid discovery of functional scFv fragments.
Nannini F, Senicar L, Parekh F, Kong KJ, Kinna A, Bughda R, Sillibourne J, Hu X, Ma B, Bai Y, Ferrari M, Pule MA, Onuoha SC.
Nannini F, et al. Among authors: bughda r.
MAbs. 2021 Jan-Dec;13(1):1864084. doi: 10.1080/19420862.2020.1864084.
MAbs. 2021.
PMID: 33382949
Free PMC article.
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An APRIL-based chimeric antigen receptor for dual targeting of BCMA and TACI in multiple myeloma.
Lee L, Draper B, Chaplin N, Philip B, Chin M, Galas-Filipowicz D, Onuoha S, Thomas S, Baldan V, Bughda R, Maciocia P, Kokalaki E, Neves MP, Patel D, Rodriguez-Justo M, Francis J, Yong K, Pule M.
Lee L, et al. Among authors: bughda r.
Blood. 2018 Feb 15;131(7):746-758. doi: 10.1182/blood-2017-05-781351. Epub 2017 Dec 28.
Blood. 2018.
PMID: 29284597
Free PMC article.
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