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Pathogenic CANVAS (AAGGG)n repeats stall DNA replication due to the formation of alternative DNA structures.
Nucleic Acids Res. 2024 May 8;52(8):4361-4374. doi: 10.1093/nar/gkae124.
Nucleic Acids Res. 2024.
PMID: 38381906
Free PMC article.
Replication dependent and independent mechanisms of GAA repeat instability.
Masnovo C, Lobo AF, Mirkin SM.
Masnovo C, et al.
DNA Repair (Amst). 2022 Oct;118:103385. doi: 10.1016/j.dnarep.2022.103385. Epub 2022 Aug 3.
DNA Repair (Amst). 2022.
PMID: 35952488
Free PMC article.
Review.
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Aurora B activity is promoted by cooperation between discrete localization sites in budding yeast.
Marsoner T, Yedavalli P, Masnovo C, Fink S, Schmitzer K, Campbell CS.
Marsoner T, et al. Among authors: masnovo c.
Mol Biol Cell. 2022 Aug 1;33(9):ar85. doi: 10.1091/mbc.E21-11-0590. Epub 2022 Jun 15.
Mol Biol Cell. 2022.
PMID: 35704464
Free PMC article.
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Rad9-mediated checkpoint activation is responsible for elevated expansions of GAA repeats in CST-deficient yeast.
Spivakovsky-Gonzalez E, Polleys EJ, Masnovo C, Cebrian J, Molina-Vargas AM, Freudenreich CH, Mirkin SM.
Spivakovsky-Gonzalez E, et al. Among authors: masnovo c.
Genetics. 2021 Oct 2;219(2):iyab125. doi: 10.1093/genetics/iyab125.
Genetics. 2021.
PMID: 34849883
Free PMC article.
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