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Anti-miRNA103/107 encapsulated in transferrin-conjugated lipid nanoparticles crosses blood-brain barrier and reduces brain ischemic damage.
Cepparulo P, Cuomo O, Campani V, Vinciguerra A, Sisalli MJ, Nele V, Anzilotti S, Valsecchi V, Casamassa A, Brancaccio P, Scorziello A, De Rosa G, Annunziato L, Pignataro G. Cepparulo P, et al. Among authors: valsecchi v. Mol Ther Nucleic Acids. 2024 Feb 2;35(1):102131. doi: 10.1016/j.omtn.2024.102131. eCollection 2024 Mar 12. Mol Ther Nucleic Acids. 2024. PMID: 38379726 Free PMC article.
Anti-miR-223-5p Ameliorates Ischemic Damage and Improves Neurological Function by Preventing NCKX2 Downregulation after Ischemia in Rats.
Cuomo O, Cepparulo P, Anzilotti S, Serani A, Sirabella R, Brancaccio P, Guida N, Valsecchi V, Vinciguerra A, Molinaro P, Formisano L, Annunziato L, Pignataro G. Cuomo O, et al. Among authors: valsecchi v. Mol Ther Nucleic Acids. 2019 Dec 6;18:1063-1071. doi: 10.1016/j.omtn.2019.10.022. Epub 2019 Oct 28. Mol Ther Nucleic Acids. 2019. PMID: 31791013 Free PMC article.
NCX1 is a new rest target gene: role in cerebral ischemia.
Formisano L, Guida N, Valsecchi V, Pignataro G, Vinciguerra A, Pannaccione A, Secondo A, Boscia F, Molinaro P, Sisalli MJ, Sirabella R, Casamassa A, Canzoniero LM, Di Renzo G, Annunziato L. Formisano L, et al. Among authors: valsecchi v. Neurobiol Dis. 2013 Feb;50:76-85. doi: 10.1016/j.nbd.2012.10.010. Epub 2012 Oct 13. Neurobiol Dis. 2013. PMID: 23069678
Transcriptional regulation of ncx1 gene in the brain.
Valsecchi V, Pignataro G, Sirabella R, Matrone C, Boscia F, Scorziello A, Sisalli MJ, Esposito E, Zambrano N, Cataldi M, Di Renzo G, Annunziato L. Valsecchi V, et al. Adv Exp Med Biol. 2013;961:137-45. doi: 10.1007/978-1-4614-4756-6_12. Adv Exp Med Biol. 2013. PMID: 23224876 Review.
Sp3/REST/HDAC1/HDAC2 Complex Represses and Sp1/HIF-1/p300 Complex Activates ncx1 Gene Transcription, in Brain Ischemia and in Ischemic Brain Preconditioning, by Epigenetic Mechanism.
Formisano L, Guida N, Valsecchi V, Cantile M, Cuomo O, Vinciguerra A, Laudati G, Pignataro G, Sirabella R, Di Renzo G, Annunziato L. Formisano L, et al. Among authors: valsecchi v. J Neurosci. 2015 May 13;35(19):7332-48. doi: 10.1523/JNEUROSCI.2174-14.2015. J Neurosci. 2015. PMID: 25972164 Free PMC article.
65 results