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Recent advances in generative biology for biotherapeutic discovery.
Trends Pharmacol Sci. 2024 Mar;45(3):255-267. doi: 10.1016/j.tips.2024.01.003. Epub 2024 Feb 19.
Trends Pharmacol Sci. 2024.
PMID: 38378385
Free article.
Review.
Development of in silico models to predict viscosity and mouse clearance using a comprehensive analytical data set collected on 83 scaffold-consistent monoclonal antibodies.
Mock M, Jacobitz AW, Langmead CJ, Sudom A, Yoo D, Humphreys SC, Alday M, Alekseychyk L, Angell N, Bi V, Catterall H, Chen CC, Chou HT, Conner KP, Cook KD, Correia AR, Dykstra A, Ghimire-Rijal S, Graham K, Grandsard P, Huh J, Hui JO, Jain M, Jann V, Jia L, Johnstone S, Khanal N, Kolvenbach C, Narhi L, Padaki R, Pelegri-O'Day EM, Qi W, Razinkov V, Rice AJ, Smith R, Spahr C, Stevens J, Sun Y, Thomas VA, van Driesche S, Vernon R, Wagner V, Walker KW, Wei Y, Winters D, Yang M, Campuzano IDG.
Mock M, et al. Among authors: grandsard p.
MAbs. 2023 Jan-Dec;15(1):2256745. doi: 10.1080/19420862.2023.2256745.
MAbs. 2023.
PMID: 37698932
Free PMC article.
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Binding affinity determination of therapeutic antibodies to membrane protein targets: Kinetic Exclusion Assay using cellular membranes for anti-CD20 antibody.
Vaish A, Lin JS, McBride HJ, Grandsard PJ, Chen Q.
Vaish A, et al. Among authors: grandsard pj.
Anal Biochem. 2020 Nov 15;609:113974. doi: 10.1016/j.ab.2020.113974. Epub 2020 Sep 30.
Anal Biochem. 2020.
PMID: 33010205
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On-chip membrane protein cell-free expression enables development of a direct binding assay: A curious case of potassium channel KcsA-Kv1.3.
Vaish A, Guo S, Murray RM, Grandsard PJ, Chen Q.
Vaish A, et al. Among authors: grandsard pj.
Anal Biochem. 2018 Sep 1;556:70-77. doi: 10.1016/j.ab.2018.06.018. Epub 2018 Jun 21.
Anal Biochem. 2018.
PMID: 29936096
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