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Ibrutinib directly reduces CD8+T cell exhaustion independent of BTK.
Li L, Zhao M, Kiernan CH, Castro Eiro MD, van Meurs M, Brouwers-Haspels I, Wilmsen MEP, Grashof DGB, van de Werken HJG, Hendriks RW, Mueller YM, Katsikis PD. Li L, et al. Among authors: kiernan ch. Front Immunol. 2023 Sep 12;14:1201415. doi: 10.3389/fimmu.2023.1201415. eCollection 2023. Front Immunol. 2023. PMID: 37771591 Free PMC article.
TLR9 plus STING Agonist Adjuvant Combination Induces Potent Neopeptide T Cell Immunity and Improves Immune Checkpoint Blockade Efficacy in a Tumor Model.
Castro Eiro MD, Hioki K, Li L, Wilmsen MEP, Kiernan CH, Brouwers-Haspels I, van Meurs M, Zhao M, de Wit H, Grashof DGB, van de Werken HJG, Mueller YM, Schliehe C, Temizoz B, Kobiyama K, Ishii KJ, Katsikis PD. Castro Eiro MD, et al. Among authors: kiernan ch. J Immunol. 2024 Feb 1;212(3):455-465. doi: 10.4049/jimmunol.2300038. J Immunol. 2024. PMID: 38063488 Free PMC article.
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