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Effectiveness of BMP-2 and PDGF-BB Adsorption onto a Collagen/Collagen-Magnesium-Hydroxyapatite Scaffold in Weight-Bearing and Non-Weight-Bearing Osteochondral Defect Bone Repair: In Vitro, Ex Vivo and In Vivo Evaluation.
Xu J, Fahmy-Garcia S, Wesdorp MA, Kops N, Forte L, De Luca C, Misciagna MM, Dolcini L, Filardo G, Labberté M, Vancíková K, Kok J, van Rietbergen B, Nickel J, Farrell E, Brama PAJ, van Osch GJVM. Xu J, et al. Among authors: brama paj. J Funct Biomater. 2023 Feb 16;14(2):111. doi: 10.3390/jfb14020111. J Funct Biomater. 2023. PMID: 36826910 Free PMC article.
Incorporating strontium enriched amorphous calcium phosphate granules in collagen/collagen-magnesium-hydroxyapatite osteochondral scaffolds improves subchondral bone repair.
Xu J, Vecstaudza J, Wesdorp MA, Labberté M, Kops N, Salerno M, Kok J, Simon M, Harmand MF, Vancíková K, van Rietbergen B, Misciagna MM, Dolcini L, Filardo G, Farrell E, van Osch GJVM, Locs J, Brama PAJ. Xu J, et al. Among authors: brama paj. Mater Today Bio. 2024 Jan 20;25:100959. doi: 10.1016/j.mtbio.2024.100959. eCollection 2024 Apr. Mater Today Bio. 2024. PMID: 38327976 Free PMC article.
Evaluation of a co-culture of rapidly isolated chondrocytes and stem cells seeded on tri-layered collagen-based scaffolds in a caprine osteochondral defect model.
Levingstone TJ, Sheehy EJ, Moran CJ, Cunniffe GM, Diaz Payno PJ, Brady RT, Almeida HV, Carroll SF, O'Byrne JM, Kelly DJ, Brama PA, O' Brien FJ. Levingstone TJ, et al. Biomater Biosyst. 2022 Oct 8;8:100066. doi: 10.1016/j.bbiosy.2022.100066. eCollection 2022 Dec. Biomater Biosyst. 2022. PMID: 36824377 Free PMC article.
Preclinical to clinical translation for intervertebral disc repair: Effects of species-specific scale, metabolism, and matrix synthesis rates on cell-based regeneration.
McDonnell EE, Wilson N, Barcellona MN, Ní Néill T, Bagnall J, Brama PAJ, Cunniffe GM, Darwish SL, Butler JS, Buckley CT. McDonnell EE, et al. Among authors: brama paj. JOR Spine. 2023 Sep 7;6(3):e1279. doi: 10.1002/jsp2.1279. eCollection 2023 Sep. JOR Spine. 2023. PMID: 37780829 Free PMC article.
Effects of two alveolar recruitment manoeuvres (sustained inflation and stepwise) followed by positive end-expiratory pressure on cardiac output (measured with lithium dilution), invasive blood pressure and arterial oxygen tension in isoflurane-anaesthetised goats.
Gómez Fernández L, Potter J, Hughes JML, Fernandez Perez C, Brama PAJ, Niimura Del Barrio MC. Gómez Fernández L, et al. Among authors: brama paj. Res Vet Sci. 2022 Dec 5;150:195-203. doi: 10.1016/j.rvsc.2022.07.004. Epub 2022 Jul 11. Res Vet Sci. 2022. PMID: 35842951 Free article.
Bilayered extracellular matrix derived scaffolds with anisotropic pore architecture guide tissue organization during osteochondral defect repair.
Browe DC, Díaz-Payno PJ, Freeman FE, Schipani R, Burdis R, Ahern DP, Nulty JM, Guler S, Randall LD, Buckley CT, Brama PAJ, Kelly DJ. Browe DC, et al. Among authors: brama paj. Acta Biomater. 2022 Apr 15;143:266-281. doi: 10.1016/j.actbio.2022.03.009. Epub 2022 Mar 9. Acta Biomater. 2022. PMID: 35278686 Free article.
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