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Page 1
Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimer's disease phenotype in mice.
Gould NL, Scherer GR, Carvalho S, Shurrush K, Kayyal H, Edry E, Elkobi A, David O, Foqara M, Thakar D, Pavesi T, Sharma V, Walker M, Maitland M, Dym O, Albeck S, Peleg Y, Germain N, Babaev I, Sharir H, Lalzar M, Shklyar B, Hazut N, Khamaisy M, Lévesque M, Lajoie G, Avoli M, Amitai G, Lefker B, Subramanyam C, Shilton B, Barr H, Rosenblum K. Gould NL, et al. J Clin Invest. 2023 Oct 2;133(19):e162120. doi: 10.1172/JCI162120. J Clin Invest. 2023. PMID: 37561584 Free PMC article.
Covalent Docking Identifies a Potent and Selective MKK7 Inhibitor.
Shraga A, Olshvang E, Davidzohn N, Khoshkenar P, Germain N, Shurrush K, Carvalho S, Avram L, Albeck S, Unger T, Lefker B, Subramanyam C, Hudkins RL, Mitchell A, Shulman Z, Kinoshita T, London N. Shraga A, et al. Cell Chem Biol. 2019 Jan 17;26(1):98-108.e5. doi: 10.1016/j.chembiol.2018.10.011. Epub 2018 Nov 15. Cell Chem Biol. 2019. PMID: 30449673 Free article.
PRMT1 inhibition induces differentiation of colon cancer cells.
Plotnikov A, Kozer N, Cohen G, Carvalho S, Duberstein S, Almog O, Solmesky LJ, Shurrush KA, Babaev I, Benjamin S, Gilad S, Kupervaser M, Levin Y, Gershovits M, Ben-Avraham D, Barr HM. Plotnikov A, et al. Among authors: shurrush ka. Sci Rep. 2020 Nov 18;10(1):20030. doi: 10.1038/s41598-020-77028-8. Sci Rep. 2020. PMID: 33208761 Free PMC article.
Optimization of Covalent MKK7 Inhibitors via Crude Nanomole-Scale Libraries.
Gehrtz P, Marom S, Bührmann M, Hardick J, Kleinbölting S, Shraga A, Dubiella C, Gabizon R, Wiese JN, Müller MP, Cohen G, Babaev I, Shurrush K, Avram L, Resnick E, Barr H, Rauh D, London N. Gehrtz P, et al. J Med Chem. 2022 Aug 11;65(15):10341-10356. doi: 10.1021/acs.jmedchem.1c02206. Epub 2022 Jul 30. J Med Chem. 2022. PMID: 35912476 Free PMC article.
Enantioselective total synthesis of macrolide (+)-neopeltolide.
Ghosh AK, Shurrush KA, Dawson ZL. Ghosh AK, et al. Among authors: shurrush ka. Org Biomol Chem. 2013 Nov 28;11(44):7768-77. doi: 10.1039/c3ob41541d. Epub 2013 Oct 11. Org Biomol Chem. 2013. PMID: 24121457 Free PMC article.