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Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner.
Mol Neurodegener. 2024 Feb 17;19(1):18. doi: 10.1186/s13024-023-00700-w.
Mol Neurodegener. 2024.
PMID: 38365827
Free PMC article.
Early modulation of the gut microbiome by female sex hormones alters amyloid pathology and microglial function.
Saha P, Weigle IQ, Slimmon N, Poli PB, Patel P, Zhang X, Cao Y, Michalkiewicz J, Gomm A, Zhang C, Tanzi RE, Dylla N, Al-Hendy A, Sisodia SS.
Saha P, et al. Among authors: weigle iq.
Sci Rep. 2024 Jan 21;14(1):1827. doi: 10.1038/s41598-024-52246-6.
Sci Rep. 2024.
PMID: 38246956
Free PMC article.
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The gut microbiome regulates astrocyte reaction to Aβ amyloidosis through microglial dependent and independent mechanisms.
Chandra S, Di Meco A, Dodiya HB, Popovic J, Cuddy LK, Weigle IQ, Zhang X, Sadleir K, Sisodia SS, Vassar R.
Chandra S, et al. Among authors: weigle iq.
Mol Neurodegener. 2023 Jul 6;18(1):45. doi: 10.1186/s13024-023-00635-2.
Mol Neurodegener. 2023.
PMID: 37415149
Free PMC article.
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Gut microbiota-driven brain Aβ amyloidosis in mice requires microglia.
Dodiya HB, Lutz HL, Weigle IQ, Patel P, Michalkiewicz J, Roman-Santiago CJ, Zhang CM, Liang Y, Srinath A, Zhang X, Xia J, Olszewski M, Zhang X, Schipma MJ, Chang EB, Tanzi RE, Gilbert JA, Sisodia SS.
Dodiya HB, et al. Among authors: weigle iq.
J Exp Med. 2022 Jan 3;219(1):e20200895. doi: 10.1084/jem.20200895. Epub 2021 Dec 2.
J Exp Med. 2022.
PMID: 34854884
Free PMC article.
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An APP ectodomain mutation outside of the Aβ domain promotes Aβ production in vitro and deposition in vivo.
Zhang X, Zhang CM, Prokopenko D, Liang Y, Zhen SY, Weigle IQ, Han W, Aryal M, Tanzi RE, Sisodia SS.
Zhang X, et al. Among authors: weigle iq.
J Exp Med. 2021 Jun 7;218(6):e20210313. doi: 10.1084/jem.20210313.
J Exp Med. 2021.
PMID: 33822840
Free PMC article.
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