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Direct quantification of in vivo mutagenesis and carcinogenesis using duplex sequencing.
Valentine CC 3rd, Young RR, Fielden MR, Kulkarni R, Williams LN, Li T, Minocherhomji S, Salk JJ. Valentine CC 3rd, et al. Among authors: salk jj. Proc Natl Acad Sci U S A. 2020 Dec 29;117(52):33414-33425. doi: 10.1073/pnas.2013724117. Epub 2020 Dec 14. Proc Natl Acad Sci U S A. 2020. PMID: 33318186 Free PMC article.
Adopting Duplex Sequencing™ Technology for Genetic Toxicity Testing: A Proof-of-Concept Mutagenesis Experiment with N-Ethyl-N-Nitrosourea (ENU)-Exposed Rats.
Smith-Roe SL, Hobbs CA, Hull V, Auman JT, Recio L, Streicker MA, Rivas MV, Pratt GA, Lo FY, Higgins JE, Schmidt EK, Williams LN, Nachmanson D, Valentine CC 3rd, Salk JJ, Witt KL. Smith-Roe SL, et al. Among authors: salk jj. bioRxiv [Preprint]. 2023 May 9:2023.05.08.539833. doi: 10.1101/2023.05.08.539833. bioRxiv. 2023. PMID: 37214853 Free PMC article. Updated. Preprint.
Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan.
Salk JJ, Loubet-Senear K, Maritschnegg E, Valentine CC, Williams LN, Higgins JE, Horvat R, Vanderstichele A, Nachmanson D, Baker KT, Emond MJ, Loter E, Tretiakova M, Soussi T, Loeb LA, Zeillinger R, Speiser P, Risques RA. Salk JJ, et al. Cell Rep. 2019 Jul 2;28(1):132-144.e3. doi: 10.1016/j.celrep.2019.05.109. Cell Rep. 2019. PMID: 31269435 Free PMC article.
Ultra-accurate Duplex Sequencing for the assessment of pretreatment ABL1 kinase domain mutations in Ph+ ALL.
Short NJ, Kantarjian H, Kanagal-Shamanna R, Sasaki K, Ravandi F, Cortes J, Konopleva M, Issa GC, Kornblau SM, Garcia-Manero G, Garris R, Higgins J, Pratt G, Williams LN, Valentine CC 3rd, Rivera VM, Pritchard J, Salk JJ, Radich J, Jabbour E. Short NJ, et al. Among authors: salk jj. Blood Cancer J. 2020 May 26;10(5):61. doi: 10.1038/s41408-020-0329-y. Blood Cancer J. 2020. PMID: 32457305 Free PMC article.
Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing.
Wang Y, Mittelstaedt RA, Wynne R, Chen Y, Cao X, Muskhelishvili L, Davis K, Robison TW, Sun W, Schmidt EK, Smith TH, Norgaard ZK, Valentine CC, Yaplee J, Williams LN, Salk JJ, Heflich RH. Wang Y, et al. Among authors: salk jj. Environ Mol Mutagen. 2021 Jun;62(5):306-318. doi: 10.1002/em.22444. Epub 2021 Jun 14. Environ Mol Mutagen. 2021. PMID: 34050964 Free PMC article.
Targeted genome fragmentation with CRISPR/Cas9 enables fast and efficient enrichment of small genomic regions and ultra-accurate sequencing with low DNA input (CRISPR-DS).
Nachmanson D, Lian S, Schmidt EK, Hipp MJ, Baker KT, Zhang Y, Tretiakova M, Loubet-Senear K, Kohrn BF, Salk JJ, Kennedy SR, Risques RA. Nachmanson D, et al. Among authors: salk jj. Genome Res. 2018 Oct;28(10):1589-1599. doi: 10.1101/gr.235291.118. Epub 2018 Sep 19. Genome Res. 2018. PMID: 30232196 Free PMC article.
185 results