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Targeting NUPR1-dependent stress granules formation to induce synthetic lethality in KrasG12D-driven tumors.
Santofimia-Castaño P, Fraunhoffer N, Liu X, Bessone IF, di Magliano MP, Audebert S, Camoin L, Estaras M, Brenière M, Modesti M, Lomberk G, Urrutia R, Soubeyran P, Neira JL, Iovanna J. Santofimia-Castaño P, et al. Among authors: modesti m. EMBO Mol Med. 2024 Mar;16(3):475-505. doi: 10.1038/s44321-024-00032-2. Epub 2024 Feb 15. EMBO Mol Med. 2024. PMID: 38360999 Free PMC article.
Catalytically inactive DNA ligase IV promotes DNA repair in living cells.
Goff NJ, Brenière M, Buehl CJ, de Melo AJ, Huskova H, Ochi T, Blundell TL, Mao W, Yu K, Modesti M, Meek K. Goff NJ, et al. Among authors: modesti m. Nucleic Acids Res. 2022 Oct 28;50(19):11058-11071. doi: 10.1093/nar/gkac913. Nucleic Acids Res. 2022. PMID: 36263813 Free PMC article.
BTN3A is a prognosis marker and a promising target for Vγ9Vδ2 T cells based-immunotherapy in pancreatic ductal adenocarcinoma (PDAC).
Benyamine A, Loncle C, Foucher E, Blazquez JL, Castanier C, Chrétien AS, Modesti M, Secq V, Chouaib S, Gironella M, Vila-Navarro E, Montalto G, Dagorn JC, Dusetti N, Iovanna J, Olive D. Benyamine A, et al. Among authors: modesti m. Oncoimmunology. 2017 Sep 21;7(1):e1372080. doi: 10.1080/2162402X.2017.1372080. eCollection 2017. Oncoimmunology. 2017. PMID: 29296524 Free PMC article.
Fluorescent Labeling of Proteins.
Modesti M. Modesti M. Methods Mol Biol. 2018;1665:115-134. doi: 10.1007/978-1-4939-7271-5_6. Methods Mol Biol. 2018. PMID: 28940066
RADX controls RAD51 filament dynamics to regulate replication fork stability.
Adolph MB, Mohamed TM, Balakrishnan S, Xue C, Morati F, Modesti M, Greene EC, Chazin WJ, Cortez D. Adolph MB, et al. Among authors: modesti m. Mol Cell. 2021 Mar 4;81(5):1074-1083.e5. doi: 10.1016/j.molcel.2020.12.036. Epub 2021 Jan 15. Mol Cell. 2021. PMID: 33453169 Free PMC article.
220 results