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Dynamic geospatial modeling of mycotoxin contamination of corn in Illinois: unveiling critical factors and predictive insights with machine learning.
Castano-Duque L, Winzeler E, Blackstock JM, Liu C, Vergopolan N, Focker M, Barnett K, Owens PR, van der Fels-Klerx HJ, Vaughan MM, Rajasekaran K. Castano-Duque L, et al. Among authors: winzeler e. Front Microbiol. 2023 Nov 1;14:1283127. doi: 10.3389/fmicb.2023.1283127. eCollection 2023. Front Microbiol. 2023. PMID: 38029202 Free PMC article.
Gradient boosting machine learning model to predict aflatoxins in Iowa corn.
Branstad-Spates EH, Castano-Duque L, Mosher GA, Hurburgh CR Jr, Owens P, Winzeler E, Rajasekaran K, Bowers EL. Branstad-Spates EH, et al. Among authors: winzeler e. Front Microbiol. 2023 Sep 1;14:1248772. doi: 10.3389/fmicb.2023.1248772. eCollection 2023. Front Microbiol. 2023. PMID: 37720139 Free PMC article.
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Xie SC, Wang Y, Morton CJ, Metcalfe RD, Dogovski C, Pasaje CFA, Dunn E, Luth MR, Kumpornsin K, Istvan ES, Park JS, Fairhurst KJ, Ketprasit N, Yeo T, Yildirim O, Bhebhe MN, Klug DM, Rutledge PJ, Godoy LC, Dey S, De Souza ML, Siqueira-Neto JL, Du Y, Puhalovich T, Amini M, Shami G, Loesbanluechai D, Nie S, Williamson N, Jana GP, Maity BC, Thomson P, Foley T, Tan DS, Niles JC, Han BW, Goldberg DE, Burrows J, Fidock DA, Lee MCS, Winzeler EA, Griffin MDW, Todd MH, Tilley L. Xie SC, et al. Among authors: winzeler ea. Nat Commun. 2024 Jan 31;15(1):937. doi: 10.1038/s41467-024-45224-z. Nat Commun. 2024. PMID: 38297033 Free PMC article.
Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases.
Wang L, Bohmer MJ, Wang J, Nardella F, Calla J, Laureano De Souza M, Schindler KA, Montejo L, Mittal N, Rocamora F, Treat M, Charlton JT, Tumwebaze PK, Rosenthal PJ, Cooper RA, Chakrabarti R, Winzeler EA, Chakrabarti D, Gray NS. Wang L, et al. Among authors: winzeler ea. J Med Chem. 2024 Jan 25;67(2):1460-1480. doi: 10.1021/acs.jmedchem.3c02046. Epub 2024 Jan 12. J Med Chem. 2024. PMID: 38214254
Antiplasmodial peptaibols act through membrane directed mechanisms.
Collins JE, Lee JW, Rocamora F, Saggu GS, Wendt KL, Pasaje CFA, Smick S, Santos NM, Paes R, Jiang T, Mittal N, Luth MR, Chin T, Chang H, McLellan JL, Morales-Hernandez B, Hanson KK, Niles JC, Desai SA, Winzeler EA, Cichewicz RH, Chakrabarti D. Collins JE, et al. Among authors: winzeler ea. Cell Chem Biol. 2024 Feb 15;31(2):312-325.e9. doi: 10.1016/j.chembiol.2023.10.025. Epub 2023 Nov 22. Cell Chem Biol. 2024. PMID: 37995692 Free PMC article.
Antimalarial drug discovery: progress and approaches.
Siqueira-Neto JL, Wicht KJ, Chibale K, Burrows JN, Fidock DA, Winzeler EA. Siqueira-Neto JL, et al. Among authors: winzeler ea. Nat Rev Drug Discov. 2023 Oct;22(10):807-826. doi: 10.1038/s41573-023-00772-9. Epub 2023 Aug 31. Nat Rev Drug Discov. 2023. PMID: 37652975 Free PMC article. Review.
236 results