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Low levels and partial exposure to palmitic acid improves mitochondrial function and the oxidative status of cultured cardiomyoblasts.
Mthembu SXH, Mazibuko-Mbeje SE, Silvestri S, Orlando P, Marcheggiani F, Cirilli I, Nkambule BB, Muller CJF, Tiano L, Dludla PV. Mthembu SXH, et al. Among authors: marcheggiani f. Toxicol Rep. 2024 Feb 2;12:234-243. doi: 10.1016/j.toxrep.2024.01.014. eCollection 2024 Jun. Toxicol Rep. 2024. PMID: 38356855 Free PMC article.
N-Acetyl cysteine ameliorates hyperglycemia-induced cardiomyocyte toxicity by improving mitochondrial energetics and enhancing endogenous Coenzyme Q9/10 levels.
Dludla PV, Orlando P, Silvestri S, Mazibuko-Mbeje SE, Johnson R, Marcheggiani F, Cirilli I, Muller CJF, Louw J, Obonye N, Nyawo T, Nkambule BB, Tiano L. Dludla PV, et al. Among authors: marcheggiani f. Toxicol Rep. 2019 Nov 5;6:1240-1245. doi: 10.1016/j.toxrep.2019.11.004. eCollection 2019. Toxicol Rep. 2019. PMID: 31799124 Free PMC article.
Palmitate-induced toxicity is associated with impaired mitochondrial respiration and accelerated oxidative stress in cultured cardiomyocytes: The critical role of coenzyme Q9/10.
Dludla PV, Silvestri S, Orlando P, Mazibuko-Mbeje SE, Johnson R, Marcheggiani F, Cirilli I, Muller CJF, Louw J, Chellan N, Obonye N, Nkambule BB, Tiano L. Dludla PV, et al. Among authors: marcheggiani f. Toxicol In Vitro. 2020 Oct;68:104948. doi: 10.1016/j.tiv.2020.104948. Epub 2020 Jul 16. Toxicol In Vitro. 2020. PMID: 32683093
Modulation of Coenzyme Q10 content and oxidative status in human dermal fibroblasts using HMG-CoA reductase inhibitor over a broad range of concentrations. From mitohormesis to mitochondrial dysfunction and accelerated aging.
Marcheggiani F, Cirilli I, Orlando P, Silvestri S, Vogelsang A, Knott A, Blatt T, Weise JM, Tiano L. Marcheggiani F, et al. Aging (Albany NY). 2019 May 10;11(9):2565-2582. doi: 10.18632/aging.101926. Aging (Albany NY). 2019. PMID: 31076563 Free PMC article.
The Combination Effect of Aspalathin and Phenylpyruvic Acid-2-O-β-D-glucoside from Rooibos against Hyperglycemia-Induced Cardiac Damage: An In Vitro Study.
Dludla PV, Muller CJF, Louw J, Mazibuko-Mbeje SE, Tiano L, Silvestri S, Orlando P, Marcheggiani F, Cirilli I, Chellan N, Ghoor S, Nkambule BB, Essop MF, Huisamen B, Johnson R. Dludla PV, et al. Among authors: marcheggiani f. Nutrients. 2020 Apr 20;12(4):1151. doi: 10.3390/nu12041151. Nutrients. 2020. PMID: 32325968 Free PMC article.
Coenzyme Q10 Supplementation Improves Adipokine Levels and Alleviates Inflammation and Lipid Peroxidation in Conditions of Metabolic Syndrome: A Meta-Analysis of Randomized Controlled Trials.
Dludla PV, Orlando P, Silvestri S, Marcheggiani F, Cirilli I, Nyambuya TM, Mxinwa V, Mokgalaboni K, Nkambule BB, Johnson R, Mazibuko-Mbeje SE, Muller CJF, Louw J, Tiano L. Dludla PV, et al. Among authors: marcheggiani f. Int J Mol Sci. 2020 May 4;21(9):3247. doi: 10.3390/ijms21093247. Int J Mol Sci. 2020. PMID: 32375340 Free PMC article. Review.
Evaluation of anticancer role of a novel ruthenium(II)-based compound compared with NAMI-A and cisplatin in impairing mitochondrial functionality and promoting oxidative stress in triple negative breast cancer models.
Silvestri S, Cirilli I, Marcheggiani F, Dludla P, Lupidi G, Pettinari R, Marchetti F, Di Nicola C, Falcioni G, Marchini C, Orlando P, Tiano L, Amici A. Silvestri S, et al. Among authors: marcheggiani f. Mitochondrion. 2021 Jan;56:25-34. doi: 10.1016/j.mito.2020.11.004. Epub 2020 Nov 19. Mitochondrion. 2021. PMID: 33220497
69 results