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Autonomous transposons tune their sequences to ensure somatic suppression.
Ilık İA, Glažar P, Tse K, Brändl B, Meierhofer D, Müller FJ, Smith ZD, Aktaş T. Ilık İA, et al. Among authors: brandl b. Nature. 2024 Feb;626(8001):1116-1124. doi: 10.1038/s41586-024-07081-0. Epub 2024 Feb 14. Nature. 2024. PMID: 38355802 Free PMC article.
Dynamic antagonism between key repressive pathways maintains the placental epigenome.
Weigert R, Hetzel S, Bailly N, Haggerty C, Ilik IA, Yung PYK, Navarro C, Bolondi A, Kumar AS, Anania C, Brändl B, Meierhofer D, Lupiáñez DG, Müller FJ, Aktas T, Elsässer SJ, Kretzmer H, Smith ZD, Meissner A. Weigert R, et al. Among authors: brandl b. Nat Cell Biol. 2023 Apr;25(4):579-591. doi: 10.1038/s41556-023-01114-y. Epub 2023 Apr 6. Nat Cell Biol. 2023. PMID: 37024684 Free PMC article.
Dnmt1 has de novo activity targeted to transposable elements.
Haggerty C, Kretzmer H, Riemenschneider C, Kumar AS, Mattei AL, Bailly N, Gottfreund J, Giesselmann P, Weigert R, Brändl B, Giehr P, Buschow R, Galonska C, von Meyenn F, Pappalardi MB, McCabe MT, Wittler L, Giesecke-Thiel C, Mielke T, Meierhofer D, Timmermann B, Müller FJ, Walter J, Meissner A. Haggerty C, et al. Among authors: brandl b. Nat Struct Mol Biol. 2021 Jul;28(7):594-603. doi: 10.1038/s41594-021-00603-8. Epub 2021 Jun 17. Nat Struct Mol Biol. 2021. PMID: 34140676 Free PMC article.
Analysis of short tandem repeat expansions and their methylation state with nanopore sequencing.
Giesselmann P, Brändl B, Raimondeau E, Bowen R, Rohrandt C, Tandon R, Kretzmer H, Assum G, Galonska C, Siebert R, Ammerpohl O, Heron A, Schneider SA, Ladewig J, Koch P, Schuldt BM, Graham JE, Meissner A, Müller FJ. Giesselmann P, et al. Among authors: brandl b. Nat Biotechnol. 2019 Dec;37(12):1478-1481. doi: 10.1038/s41587-019-0293-x. Epub 2019 Nov 18. Nat Biotechnol. 2019. PMID: 31740840
Enhanced cortical neural stem cell identity through short SMAD and WNT inhibition in human cerebral organoids facilitates emergence of outer radial glial cells.
Rosebrock D, Arora S, Mutukula N, Volkman R, Gralinska E, Balaskas A, Aragonés Hernández A, Buschow R, Brändl B, Müller FJ, Arndt PF, Vingron M, Elkabetz Y. Rosebrock D, et al. Among authors: brandl b. Nat Cell Biol. 2022 Jun;24(6):981-995. doi: 10.1038/s41556-022-00929-5. Epub 2022 Jun 13. Nat Cell Biol. 2022. PMID: 35697781 Free PMC article.
Generation of two human isogenic iPSC lines from fetal dermal fibroblasts.
Tandon R, Brändl B, Baryshnikova N, Landshammer A, Steenpaß L, Keminer O, Pless O, Müller FJ. Tandon R, et al. Among authors: brandl b. Stem Cell Res. 2018 Dec;33:120-124. doi: 10.1016/j.scr.2018.10.004. Epub 2018 Oct 12. Stem Cell Res. 2018. PMID: 30343101 Free article.
Generation of an induced pluripotent stem cell line, ZIPi021-A, from fibroblasts of a Prader-Willi syndrome patient with maternal uniparental disomy (mUPD).
Heseding H, Jahn K, Brändl B, Haase A, Shum IO, Kohrn T, Bleich S, Frieling H, Martin U, Müller FJ, Wunderlich S, Deest M. Heseding H, et al. Among authors: brandl b. Stem Cell Res. 2023 Sep;71:103143. doi: 10.1016/j.scr.2023.103143. Epub 2023 Jun 14. Stem Cell Res. 2023. PMID: 37343429 Free article.
70 results