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Inflammation and NLRP3 Inflammasome Activation Initiated in Response to Pressure Overload by Ca2+/Calmodulin-Dependent Protein Kinase II δ Signaling in Cardiomyocytes Are Essential for Adverse Cardiac Remodeling.
Suetomi T, Willeford A, Brand CS, Cho Y, Ross RS, Miyamoto S, Brown JH. Suetomi T, et al. Among authors: willeford a. Circulation. 2018 Nov 27;138(22):2530-2544. doi: 10.1161/CIRCULATIONAHA.118.034621. Circulation. 2018. PMID: 30571348 Free PMC article.
Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice.
Crotty Alexander LE, Drummond CA, Hepokoski M, Mathew D, Moshensky A, Willeford A, Das S, Singh P, Yong Z, Lee JH, Vega K, Du A, Shin J, Javier C, Tian J, Brown JH, Breen EC. Crotty Alexander LE, et al. Among authors: willeford a. Am J Physiol Regul Integr Comp Physiol. 2018 Jun 1;314(6):R834-R847. doi: 10.1152/ajpregu.00270.2017. Epub 2018 Jan 31. Am J Physiol Regul Integr Comp Physiol. 2018. PMID: 29384700 Free PMC article.
CaMKIIδ mediates β-adrenergic effects on RyR2 phosphorylation and SR Ca(2+) leak and the pathophysiological response to chronic β-adrenergic stimulation.
Grimm M, Ling H, Willeford A, Pereira L, Gray CB, Erickson JR, Sarma S, Respress JL, Wehrens XH, Bers DM, Brown JH. Grimm M, et al. Among authors: willeford a. J Mol Cell Cardiol. 2015 Aug;85:282-91. doi: 10.1016/j.yjmcc.2015.06.007. Epub 2015 Jun 14. J Mol Cell Cardiol. 2015. PMID: 26080362 Free PMC article.