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Differential Responses to Immune Checkpoint Inhibitors are Governed by Diverse Mismatch Repair Gene Alterations.
Khushman MM, Toboni MD, Xiu J, Manne U, Farrell A, Lou E, Shields AF, Philip PA, Salem ME, Abraham J, Spetzler D, Marshall J, Jayachandran P, Hall MJ, Lenz HJ, Sahin IH, Seeber A, Powell MA. Khushman MM, et al. Among authors: manne u. Clin Cancer Res. 2024 May 1;30(9):1906-1915. doi: 10.1158/1078-0432.CCR-23-3004. Clin Cancer Res. 2024. PMID: 38350001
DCZ0415, a small-molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β-catenin pathway in colorectal cancer.
Agarwal S, Afaq F, Bajpai P, Kim HG, Elkholy A, Behring M, Chandrashekar DS, Diffalha SA, Khushman M, Sugandha SP, Varambally S, Manne U. Agarwal S, et al. Among authors: manne u. Mol Oncol. 2022 Apr;16(8):1728-1745. doi: 10.1002/1878-0261.13201. Epub 2022 Mar 7. Mol Oncol. 2022. PMID: 35194944 Free PMC article.
BZW2 Inhibition Reduces Colorectal Cancer Growth and Metastasis.
Agarwal S, Afaq F, Bajpai P, Behring M, Kim HG, Varambally A, Chandrashekar DS, Peter S, Diffalha SA, Khushman M, Seeber A, Varambally S, Manne U. Agarwal S, et al. Among authors: manne u. Mol Cancer Res. 2023 Jul 5;21(7):698-712. doi: 10.1158/1541-7786.MCR-23-0003. Mol Cancer Res. 2023. PMID: 37067340 Free PMC article.
158 results