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Kisspeptin-10 binding to Gpr54 in osteoclasts prevents bone loss by activating Dusp18-mediated dephosphorylation of Src.
Li Z, Yang X, Fu R, Wu Z, Xu S, Jiao J, Qian M, Zhang L, Wu C, Xie T, Yao J, Wu Z, Li W, Ma G, You Y, Chen Y, Zhang HK, Cheng Y, Tang X, Wu P, Lian G, Wei H, Zhao J, Xu J, Ai L, Siwko S, Wang Y, Ding J, Song G, Luo J, Liu M, Xiao J. Li Z, et al. Among authors: xu s, xu j. Nat Commun. 2024 Feb 12;15(1):1300. doi: 10.1038/s41467-024-44852-9. Nat Commun. 2024. PMID: 38346942 Free PMC article.
Leucine-rich repeat-containing G protein-coupled receptor 4 facilitates vesicular stomatitis virus infection by binding vesicular stomatitis virus glycoprotein.
Zhang N, Huang H, Tan B, Wei Y, Xiong Q, Yan Y, Hou L, Wu N, Siwko S, Cimarelli A, Xu J, Han H, Qian M, Liu M, Du B. Zhang N, et al. Among authors: xu j. J Biol Chem. 2017 Oct 6;292(40):16527-16538. doi: 10.1074/jbc.M117.802090. Epub 2017 Aug 23. J Biol Chem. 2017. PMID: 28842478 Free PMC article.
Reply to: Binding site for MDL-801 on SIRT6.
Huang Z, Zhao J, Deng W, Chen Y, Shang J, Song K, Zhang L, Wang C, Lu S, Yang X, He B, Min J, Hu H, Tan M, Xu J, Zhang Q, Zhong J, Sun X, Mao Z, Lin H, Xiao M, Chin YE, Jiang H, Shen H, Xu Y, Chen G, Zhang J. Huang Z, et al. Among authors: xu y, xu j. Nat Chem Biol. 2021 May;17(5):522-523. doi: 10.1038/s41589-021-00750-5. Epub 2021 Mar 1. Nat Chem Biol. 2021. PMID: 33649600 No abstract available.
Direct SUMOylation of M1 muscarinic acetylcholine receptor increases its ligand-binding affinity and signal transduction.
Xu J, Tan P, Li H, Cui Y, Qiu Y, Wang H, Zhang X, Li J, Zhu L, Zhou W, Chen H. Xu J, et al. FASEB J. 2019 Mar;33(3):3237-3251. doi: 10.1096/fj.201800936R. Epub 2018 Nov 8. FASEB J. 2019. PMID: 30407877
Our results provide evidence that M1 SUMOylation is an important PTM involved in regulation of the affinity for agonists and for activation of signaling pathways.-Xu, J., Tan, P., Li, H., Cui, Y., Qiu, Y., Wang, H., Zhang, X., Li, J., Zhu, L., Zhou, W., Chen, …
Our results provide evidence that M1 SUMOylation is an important PTM involved in regulation of the affinity for agonists and for activation …
M1 muscarinic receptors regulate the phosphorylation of AMPA receptor subunit GluA1 via a signaling pathway linking cAMP-PKA and PI3K-Akt.
Zhao LX, Ge YH, Li JB, Xiong CH, Law PY, Xu JR, Qiu Y, Chen HZ. Zhao LX, et al. FASEB J. 2019 May;33(5):6622-6631. doi: 10.1096/fj.201802351R. Epub 2019 Feb 22. FASEB J. 2019. PMID: 30794430
Taken together, these data demonstrate that M1 receptor activation induces membrane insertion of GluA1 via a signaling linking cAMP-PKA and PI3K-Akt-mTOR pathways but is irrelevant to protein synthesis.-Zhao, L.-X., Ge, Y.-H., Li, J.-B., Xiong, C.-H., Law, P.-Y., Xu …
Taken together, these data demonstrate that M1 receptor activation induces membrane insertion of GluA1 via a signaling linking cAMP-PKA and …
62,201 results
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