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Evidence supports a causal association between allele-specific vitamin D receptor binding and multiple sclerosis among Europeans.
Adams C, Manouchehrinia A, Quach HL, Quach DL, Olsson T, Kockum I, Schaefer C, Ponting CP, Alfredsson L, Barcellos LF. Adams C, et al. Among authors: quach dl. Proc Natl Acad Sci U S A. 2024 Feb 20;121(8):e2302259121. doi: 10.1073/pnas.2302259121. Epub 2024 Feb 12. Proc Natl Acad Sci U S A. 2024. PMID: 38346204 Free PMC article.
Evidence for a causal relationship between low vitamin D, high BMI, and pediatric-onset MS.
Gianfrancesco MA, Stridh P, Rhead B, Shao X, Xu E, Graves JS, Chitnis T, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Mar S, Kahn I, Rose J, Roalstad S, Casper TC, Shen L, Quach H, Quach D, Hillert J, Bäärnhielm M, Hedstrom A, Olsson T, Kockum I, Alfredsson L, Metayer C, Schaefer C, Barcellos LF, Waubant E; Network of Pediatric Multiple Sclerosis Centers. Gianfrancesco MA, et al. Neurology. 2017 Apr 25;88(17):1623-1629. doi: 10.1212/WNL.0000000000003849. Epub 2017 Mar 29. Neurology. 2017. PMID: 28356466 Free PMC article.
Genetic risk factors for pediatric-onset multiple sclerosis.
Gianfrancesco MA, Stridh P, Shao X, Rhead B, Graves JS, Chitnis T, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Mar S, Kahn I, Rose J, Roalstad S, Casper TC, Shen L, Quach H, Quach D, Hillert J, Hedstrom A, Olsson T, Kockum I, Alfredsson L, Schaefer C, Barcellos LF, Waubant E; Network of Pediatric Multiple Sclerosis Centers. Gianfrancesco MA, et al. Mult Scler. 2018 Dec;24(14):1825-1834. doi: 10.1177/1352458517733551. Epub 2017 Oct 5. Mult Scler. 2018. PMID: 28980494 Free PMC article.
Rare and low-frequency coding genetic variants contribute to pediatric-onset multiple sclerosis.
Horton MK, Shim JE, Wallace A, Graves JS, Aaen G, Greenberg B, Mar S, Wheeler Y, Weinstock-Guttman B, Waldman A, Schreiner T, Rodriguez M, Tillema JM, Chitnis T, Krupp L, Casper TC, Rensel M, Hart J, Quach HL, Quach DL, Schaefer C, Waubant E, Barcellos LF. Horton MK, et al. Among authors: quach dl. Mult Scler. 2023 Apr;29(4-5):505-511. doi: 10.1177/13524585221150736. Epub 2023 Feb 8. Mult Scler. 2023. PMID: 36755464 Free PMC article.
miRNA contributions to pediatric-onset multiple sclerosis inferred from GWAS.
Rhead B, Shao X, Graves JS, Chitnis T, Waldman AT, Lotze T, Schreiner T, Belman A, Krupp L, Greenberg BM, Weinstock-Guttman B, Aaen G, Tillema JM, Rodriguez M, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee MS, Gorman M, Benson L, Mar S, Kahn I, Rose J, Casper TC, Quach H, Quach D, Schaefer C, Waubant E, Barcellos LF; US Network of Pediatric MS Centers. Rhead B, et al. Ann Clin Transl Neurol. 2019 May 15;6(6):1053-1061. doi: 10.1002/acn3.786. eCollection 2019 Jun. Ann Clin Transl Neurol. 2019. PMID: 31211169 Free PMC article.
High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.
Barcellos LF, May SL, Ramsay PP, Quach HL, Lane JA, Nititham J, Noble JA, Taylor KE, Quach DL, Chung SA, Kelly JA, Moser KL, Behrens TW, Seldin MF, Thomson G, Harley JB, Gaffney PM, Criswell LA. Barcellos LF, et al. Among authors: quach dl. PLoS Genet. 2009 Oct;5(10):e1000696. doi: 10.1371/journal.pgen.1000696. Epub 2009 Oct 23. PLoS Genet. 2009. PMID: 19851445 Free PMC article.
Identification of Cell-Specific Differential DNA Methylation Associated With Methotrexate Treatment Response in Rheumatoid Arthritis.
Adams C, Nair N, Plant D, Verstappen SMM, Quach HL, Quach DL, Carvidi A, Nititham J, Nakamura M, Graf J, Barton A, Criswell LA, Barcellos LF. Adams C, et al. Among authors: quach dl. Arthritis Rheumatol. 2023 Jul;75(7):1088-1097. doi: 10.1002/art.42464. Epub 2023 May 9. Arthritis Rheumatol. 2023. PMID: 36716083 Free PMC article.
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