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BRCA1/Trp53 heterozygosity and replication stress drive esophageal cancer development in a mouse model.
He Y, Rivera J, Diossy M, Duan H, Bowman-Colin C, Reed R, Jennings R, Novak J, Tran SV, Cohen EF, Szuts D, Giobbie-Hurder A, Bronson RT, Bass AJ, Signoretti S, Szallasi Z, Livingston DM, Pathania S. He Y, et al. Among authors: tran sv. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41):e2108421118. doi: 10.1073/pnas.2108421118. Proc Natl Acad Sci U S A. 2021. PMID: 34607954 Free PMC article.
Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.
Monticelli LA, Buck MD, Flamar AL, Saenz SA, Tait Wojno ED, Yudanin NA, Osborne LC, Hepworth MR, Tran SV, Rodewald HR, Shah H, Cross JR, Diamond JM, Cantu E, Christie JD, Pearce EL, Artis D. Monticelli LA, et al. Among authors: tran sv. Nat Immunol. 2016 Jun;17(6):656-65. doi: 10.1038/ni.3421. Epub 2016 Apr 4. Nat Immunol. 2016. PMID: 27043409 Free PMC article.
Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut.
Howitt MR, Lavoie S, Michaud M, Blum AM, Tran SV, Weinstock JV, Gallini CA, Redding K, Margolskee RF, Osborne LC, Artis D, Garrett WS. Howitt MR, et al. Among authors: tran sv. Science. 2016 Mar 18;351(6279):1329-33. doi: 10.1126/science.aaf1648. Epub 2016 Feb 4. Science. 2016. PMID: 26847546 Free PMC article.
Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.
Osborne LC, Monticelli LA, Nice TJ, Sutherland TE, Siracusa MC, Hepworth MR, Tomov VT, Kobuley D, Tran SV, Bittinger K, Bailey AG, Laughlin AL, Boucher JL, Wherry EJ, Bushman FD, Allen JE, Virgin HW, Artis D. Osborne LC, et al. Among authors: tran sv. Science. 2014 Aug 1;345(6196):578-82. doi: 10.1126/science.1256942. Epub 2014 Jul 17. Science. 2014. PMID: 25082704 Free PMC article.
11 results