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Pharmacological evaluation of the anxiolytic-like effects of EMD 386088, a partial 5-HT6 receptor agonist, in the rat elevated plus-maze and Vogel conflict tests.
Jastrzębska-Więsek M, Siwek A, Partyka A, Kubacka M, Mogilski S, Wasik A, Kołaczkowski M, Wesołowska A. Jastrzębska-Więsek M, et al. Among authors: siwek a. Neuropharmacology. 2014 Oct;85:253-62. doi: 10.1016/j.neuropharm.2014.05.036. Epub 2014 Jun 4. Neuropharmacology. 2014. PMID: 24905144
Novel 5-HT6 receptor antagonists/D2 receptor partial agonists targeting behavioral and psychological symptoms of dementia.
Kołaczkowski M, Marcinkowska M, Bucki A, Śniecikowska J, Pawłowski M, Kazek G, Siwek A, Jastrzębska-Więsek M, Partyka A, Wasik A, Wesołowska A, Mierzejewski P, Bienkowski P. Kołaczkowski M, et al. Among authors: siwek a. Eur J Med Chem. 2015 Mar 6;92:221-35. doi: 10.1016/j.ejmech.2014.12.045. Epub 2014 Dec 24. Eur J Med Chem. 2015. PMID: 25557493
Structure-activity relationships and molecular studies of novel arylpiperazinylalkyl purine-2,4-diones and purine-2,4,8-triones with antidepressant and anxiolytic-like activity.
Zagórska A, Kołaczkowski M, Bucki A, Siwek A, Kazek G, Satała G, Bojarski AJ, Partyka A, Wesołowska A, Pawłowski M. Zagórska A, et al. Among authors: siwek a. Eur J Med Chem. 2015 Jun 5;97:142-54. doi: 10.1016/j.ejmech.2015.04.046. Epub 2015 May 1. Eur J Med Chem. 2015. PMID: 25965777
Antidepressant-like activity of EMD 386088, a 5-HT6 receptor partial agonist, following systemic acute and chronic administration to rats.
Jastrzębska-Więsek M, Siwek A, Partyka A, Szewczyk B, Sowa-Kućma M, Wasik A, Kołaczkowski M, Wesołowska A. Jastrzębska-Więsek M, et al. Among authors: siwek a. Naunyn Schmiedebergs Arch Pharmacol. 2015 Oct;388(10):1079-88. doi: 10.1007/s00210-015-1141-2. Epub 2015 Jun 16. Naunyn Schmiedebergs Arch Pharmacol. 2015. PMID: 26077660
Antidepressant- and Anxiolytic-Like Effects of New Dual 5-HT₁A and 5-HT₇ Antagonists in Animal Models.
Pytka K, Partyka A, Jastrzębska-Więsek M, Siwek A, Głuch-Lutwin M, Mordyl B, Kazek G, Rapacz A, Olczyk A, Gałuszka A, Błachuta M, Waszkielewicz A, Marona H, Sapa J, Filipek B, Wesołowska A. Pytka K, et al. Among authors: siwek a. PLoS One. 2015 Nov 10;10(11):e0142499. doi: 10.1371/journal.pone.0142499. eCollection 2015. PLoS One. 2015. PMID: 26554929 Free PMC article.
190 results